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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Onono, Maricianah
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document
Post-randomization differences in condomless vaginal sex among women randomized to DMPA-IM, copper IUD and levonorgestrel implant in the ECHO trial
Abstract
PU06.02<br/>The Evidence for Contraceptive Options and HIV Outcomes (ECHO) trial found no substantial difference in HIV acquisition risk between women randomised to injectable depot medroxyprogesterone acetate (DMPA-IM), copper intrauterine device (Cu-IUD) or the levonorgestrel (LNG) implant. However, post-randomization differences in some self-reported sexual behaviors by randomized contraceptive method were reported.This nested sub-study evaluated differences in condomless vaginal sex post-randomization by study arm by testing for prostate-specific antigen (PSA). The results suggest that the frequency of condomless sex may have differed by randomized contraceptive method among participants, potentially reflecting biolgoical changes induced by the contraceptive methods and/or differential concerns about HIV risk.