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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Chagnon, Grégory
Université Grenoble Alpes
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (28/28 displayed)
- 2020Anisotropy and Clausius-Clapeyron relation for forward and reverse stress-induced martensitic transformations in polycrystalline NiTi thin walled tubescitations
- 2020A comprehensive thermo-viscoelastic experimental investigation of Ecoflex polymercitations
- 2019Strain Gauges Based 3D Shape Monitoring of Beam Structures Using Finite Width Gauge Modelcitations
- 2019Characterizing Transformation Phenomena and Elastic Moduli of Austenite and Oriented Martensite of Superelastic Thin NiTi Wire through Isothermal Dynamic Mechanical Analysiscitations
- 2018Anisotropy and temperature dependence of superelastic behavior of NiTi shape memory alloy thin walled tubes
- 2018Mechanical and radiological behavior of a bioresorbable polymer during in vivo degradation. An in vivo rat study to develop an Internal biliary stent to reduce biliary complications after liver transplantation
- 2018Geometry-based model for U-shaped strain gauges on medical needles
- 2017Anisotropic tensile behavior of NiTi Tubes and its dependence on temperature experimental results
- 2016Modelling of mechanical properties of a PLA-b-PEG-b-PLA biodegradable triblock copolymer during hydrolytic degradation
- 2016Anisotropic thermomechanical properties of a superelastic Nickel-Titane thin tube
- 2015Radiopaque poly(ε-caprolactone) as additive for X-ray imaging of temporary implantable medical devicescitations
- 2015Study of electropulse heat treatment of cold worked NiTi wire: From uniform to localised tensile behaviourcitations
- 2015Mechanically-architectured silicone elastomer membranes for biomedical applications
- 2014A conical mandrel tube drawing test designed to assess failure criteriacitations
- 2014Mechanical characterization and comparison of different NiTi/silicone rubber interfacescitations
- 2013Design of specific experimental tests to evaluate formability prediction of cold drawing CoCr Tubes
- 2012Mechanical behaviour of architectured NiTi materials in complex loading
- 2012Mechanical behaviour of architectured NiTi materials in complex loading
- 2012Experiments and modeling of smart silicone elastomer membranes reinforced with shaped NiTi textiles
- 2011Simulation of Drawing of Small Stainless Steel Platinum Medical Tubes-Influence of the Tool Parameters on the Forming Limitcitations
- 2009Thermomechanical modelling of cold drawing processes of small diameter tubes
- 2007Tube Drawing Process Modelling By A Finite Element Analysis
- 2007Tube Drawing Process Modelling By A Finite Element Analysis
- 2007Modélisation de l'étirage à froid de tubes par analyse éléments-finis
- 2004Theoretical and numerical limitations for the simulation of crack propagation in natural rubber components
- 2003Theoretical and numerical limitations for the simulation of crack propagation in natural rubber components
- 2003Crack initiation in filled natural rubber: experimental database and macroscopic observations
- 2002Influence of the loading conditions on fatigue properties for filled elastomers
Places of action
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document
Modelling of mechanical properties of a PLA-b-PEG-b-PLA biodegradable triblock copolymer during hydrolytic degradation
Abstract
PLA-based biodegradable copolymers are used in many biomedical applications such as temporary implantable devices. Especially, PLA-b-PEG-b-PLA is an excellent candidate for tissue engineering applications. Indeed, it has a good biocompatibility and possesses both mechanical properties of PLA and hydrophilicity of PEG, allowing good properties and degradation time modulation. The main degradation process, for this type of polymers is the hydrolysis of ester links. After the diffusion of water into the polymer bulk, the hydrolysis reaction breaks the polymeric bonds. Modelling of mechanical properties evolution of biodegradable polymers is essential in order to design devices.The aim of this study is to explore and model the viscoelastic properties evolution of a PLA-b-PEG-b-PLA biodegradable copolymer during hydrolytic degradation. The mass decrease, the number average molecular weight and the mechanical properties were studied during 7 degradation weeks. Tensile and relaxation tests in a liquid bath at 37°C were realized at different states of degradation. Stress relaxation is observed, highlighting a viscoelastic behavior for every degradation state. Moreover, the polymer suffers a loss of mechanical properties in the course of degradation. In order to model viscoelastic properties, a generalized Maxwell model is used. This model is first identified on results obtained for non degraded material. Then, based on the invariance of the normalized relaxation curves experimentally observed for the degraded materials, a degradation variable is introduced in the model. Predictions of the model are then compared to experimental results in the course of degradation. The abilities and limits of the model are discussed.