| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Bendjemil, Badis
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (8/8 displayed)
- 2023Synthesis of TiC(1-x)–ZrCx (x=0.2) composite by FAST-SPS-FCT technology, effect of SWCNTs and nano-WC additions on structural properties: Application for ballistic protection
- 2020Study of the Nanocomposite Mo2C(1-x)-TiC(x)-SWCNTs by Field Actived Sparck Plasma Sintering Process’
- 2020Study of the Nanocomposite cBN/TiC-SWCNTs by Field Actived Sparck Plasma Sintering Process
- 2020‘Study of the High Performance Ceramic-Matrix Composites (CMC’s) byCombustion in the TiO2-Al-C System’
- 2020‘Study of the Nanocomposite cBN/TiC-SWCNTs by Field Actived Sparck Plasma Sintering Process’
- 2019Carbon Nanostructures in Cancer Diagnosis and Therapy
- 2014Crystallization Kinetics and Magnetic Properties of Fe40Ni40B20 Amorphous Ribboncitations
- 2012Crystallization Behavior of Fe50−xCr15Mo14C15B6Mx (x = 0, 2 and M=Y, Gd) Bulk Metallic Glasses and Ribbons by in situ High Temperature X-Ray Diffractioncitations
Places of action
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article
Carbon Nanostructures in Cancer Diagnosis and Therapy
Abstract
Duringthe past years, carbon nanotubes (CNTs) have attracted considerable interest sincetheir first discovery. great progress has been made in the field of nanomaterials given their great potential in biomedical applications. Carbon nanotubes (CNTs), due to their unique physicochemical properties, have become a popular tool in cancer diagnosis and therapy. They are considered one of the most promising nanomaterials with the capability of both detectingthecancerouscellsanddeliveringdrugsorsmall therapeuticmoleculestothesecellsBecauseofthe unique structure, extremely high specific surface area to-volume ratio enables them to use in an intense real time applicationssuchasdetectionandtreatmentofcancerouscells,nervousdisorders,tissuerepair.andexcellent electrical and mechanical properties carbon nanotubes composed of excellent mechanical strength, electrical and thermalconductivitiesmakesthemasuitablesubstancetowarddevelopingmedicaldevices.,CNTshavebeen exploredinalmosteverysinglecancertreatmentmodality,includingdrugdeliverywithsmallnanomolecules, lymphatic targeted chemotherapy, thermal therapy, photodynamic therapy, and gene therapy and demonstrate a greatpromiseintheiruseintargeteddrugdeliverysystems,diagnostictechniquesandinbio-analytical applications. Majority of the biomedical applications of CNTs must be used after successful functionalization for morepotentialapplicationsthanpristineCNTs.ThereareseveralapproachestomodifypristineCNTsto potentiallyactive.CNTspoisedintothehumanlifeandexploitedinmedicalcontext.Herein,wereviewedthe followingtopics(i)FunctionalizationofCNTs(ii)CNTsinrealtimeapplicationssuchasdrugdelivery,gene therapy, biosensors and bio imaging; (iii) CNTs 3D printed scaffolds for medicine and (iv) Biocompatability and Biodegradability.Single-walledcarbonnanotubes(SWCNTs)weresynthesizedusingthehigh-pressurecarbon monoxide disproportionation process (HiPCO). The SWCNT diameter, diameter distribution and yield can be varied dependingontheprocessparameters.TheobtainedHiPCOproductpresentanironnanoparticleencapsulated heteronanocarbon(core-shellnanoparticles)atlowpressure(1bar)afterremovingofironmetal catalyst nanoparticle and amorphous carbon by acid immersion and oxidation. The resultingtherapeutic molecule in the form of core-shell nanoparticles and single walled carbon nanotubes after functionalization by filling of iron can beuseastherapeuticnanomaterialsinnanomedicineindiagnosisandtreatmentofcancertumor.Thispaper describesthesynthesismethodandroleofmultifunctionalnanoparticleindiagnosisandtreatmentofcancer. Therefore, the aim of this review is to provide basic information on nanoparticles, describe previously developed methods to functionalize nanoparticles and discuss theirpotential applications innanobiomedical and mention thetherapeuticnanoparticlelargescaleproductionandcommercializationchallenges.Inthefinalpartofthe review, emphasis is given on the pharmacokinetic aspects of carbon nanotubes includingadministration routes, absorption mechanisms, distribution and elimination of carbon nanotubes based systems. Lastly, a comprehensive account aboutthe potential biomedical applications hasbeen givenfollowed by insightsinto the future carbon nanotubes from synthesis to in vivo biomedical applications.