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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Cleymand, Franck
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (15/15 displayed)
- 2021Comparison of the Physicochemical Properties of Chitin Extracted from Cicada orni Sloughs Harvested in Three Different Years and Characterization of the Resulting Chitosancitations
- 2021Study of the influence of autoclave sterilization on the properties of citrate functionalized iron oxide nanoparticlescitations
- 2020Gelatin Methacryloyl (GelMA) Nanocomposite Hydrogels Embedding Bioactive Naringin Liposomescitations
- 2019Carbon Nanostructures in Cancer Diagnosis and Therapy
- 2018Chemical environment and functional properties of highly crystalline ZnSnN2 thin films deposited by reactive sputtering at room temperaturecitations
- 2017Multilayered membranes with tuned well arrays to be used as regenerative patchescitations
- 2017Synthesis and Characterization of Nanofunctionalized Gelatin Methacrylate Hydrogelscitations
- 2017Synthesis and Characterization of Nanofunctionalized Gelatin Methacrylate Hydrogelscitations
- 2015Influence of recasting on the quality of dental alloys: A systematic review
- 2014Evaluation of Elastic and Plastic Properties of Ni50Al50(at. (%)) and (Ni-40,Pt-10)Al-50(at. %) Single Crystals Oriented by Means of Scanning Acoustic Microscopy and Depth Sensing Indentation
- 2014Local modification of the microstructure and electrical properties of multifunctional Au-YSZ nanocomposite thin films by laser interference patterningcitations
- 2013Structural and mechanical multi-scale characterization of white New-Zealand rabbit Achilles tendoncitations
- 2013Structural and mechanical multi-scale characterization of white New-Zealand rabbit Achilles tendoncitations
- 2013Effects of Ar-N-2-O-2 Microwave Plasma on Poly-L-Lactic Acid Thin Films Designed for Tissue Engineeringcitations
- 2011Stainless steel patterning by combination of micro-patterning and driven strain produced by plasma assisted nitridingcitations
Places of action
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article
Carbon Nanostructures in Cancer Diagnosis and Therapy
Abstract
Duringthe past years, carbon nanotubes (CNTs) have attracted considerable interest sincetheir first discovery. great progress has been made in the field of nanomaterials given their great potential in biomedical applications. Carbon nanotubes (CNTs), due to their unique physicochemical properties, have become a popular tool in cancer diagnosis and therapy. They are considered one of the most promising nanomaterials with the capability of both detectingthecancerouscellsanddeliveringdrugsorsmall therapeuticmoleculestothesecellsBecauseofthe unique structure, extremely high specific surface area to-volume ratio enables them to use in an intense real time applicationssuchasdetectionandtreatmentofcancerouscells,nervousdisorders,tissuerepair.andexcellent electrical and mechanical properties carbon nanotubes composed of excellent mechanical strength, electrical and thermalconductivitiesmakesthemasuitablesubstancetowarddevelopingmedicaldevices.,CNTshavebeen exploredinalmosteverysinglecancertreatmentmodality,includingdrugdeliverywithsmallnanomolecules, lymphatic targeted chemotherapy, thermal therapy, photodynamic therapy, and gene therapy and demonstrate a greatpromiseintheiruseintargeteddrugdeliverysystems,diagnostictechniquesandinbio-analytical applications. Majority of the biomedical applications of CNTs must be used after successful functionalization for morepotentialapplicationsthanpristineCNTs.ThereareseveralapproachestomodifypristineCNTsto potentiallyactive.CNTspoisedintothehumanlifeandexploitedinmedicalcontext.Herein,wereviewedthe followingtopics(i)FunctionalizationofCNTs(ii)CNTsinrealtimeapplicationssuchasdrugdelivery,gene therapy, biosensors and bio imaging; (iii) CNTs 3D printed scaffolds for medicine and (iv) Biocompatability and Biodegradability.Single-walledcarbonnanotubes(SWCNTs)weresynthesizedusingthehigh-pressurecarbon monoxide disproportionation process (HiPCO). The SWCNT diameter, diameter distribution and yield can be varied dependingontheprocessparameters.TheobtainedHiPCOproductpresentanironnanoparticleencapsulated heteronanocarbon(core-shellnanoparticles)atlowpressure(1bar)afterremovingofironmetal catalyst nanoparticle and amorphous carbon by acid immersion and oxidation. The resultingtherapeutic molecule in the form of core-shell nanoparticles and single walled carbon nanotubes after functionalization by filling of iron can beuseastherapeuticnanomaterialsinnanomedicineindiagnosisandtreatmentofcancertumor.Thispaper describesthesynthesismethodandroleofmultifunctionalnanoparticleindiagnosisandtreatmentofcancer. Therefore, the aim of this review is to provide basic information on nanoparticles, describe previously developed methods to functionalize nanoparticles and discuss theirpotential applications innanobiomedical and mention thetherapeuticnanoparticlelargescaleproductionandcommercializationchallenges.Inthefinalpartofthe review, emphasis is given on the pharmacokinetic aspects of carbon nanotubes includingadministration routes, absorption mechanisms, distribution and elimination of carbon nanotubes based systems. Lastly, a comprehensive account aboutthe potential biomedical applications hasbeen givenfollowed by insightsinto the future carbon nanotubes from synthesis to in vivo biomedical applications.