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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Gauthier, Rémy
French National Centre for Scientific Research
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (6/6 displayed)
- 2022Experimental Investigation of Dental Composites Degradation After Early Water Exposurecitations
- 2022Toxicological Risks of the Cobalt–Chromium Alloys in Dentistry: A Systematic Reviewcitations
- 2019Anisotropic elastic properties of human femoral cortical bone and relationships with composition and microstructure in elderlycitations
- 2017Strain rate influence on human cortical bone toughness: A comparative study of four paired anatomical sitescitations
- 2017Three-dimensional imaging of crack propagation mechanisms in human cortical bone on three paired anatomical locations
- 2016Fabrication and Assembly of the $Nb_3Sn$ Dipole Magnet FRESCA2citations
Places of action
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conferencepaper
Three-dimensional imaging of crack propagation mechanisms in human cortical bone on three paired anatomical locations
Abstract
The comprehension of crack propagation mechanisms in human cortical bone is of great importance for the improvement of fracture risk prediction. It is known that crack advance can be slowed down by toughening mechanisms, such as micro-damage formation near the crack tip. These mechanisms are thought to be related to bone microstructure. Recent results showed that under low loading rate, the radius diaphysis resisted better to crack propagation than the femoral diaphysis or neck (Gauthier et al., JMBBM, 2017). X-Ray CT imaging at the microscopic scale (µCT) is a standard method for the assessment of human cortical bone architecture but the assessment of micro-damage requires sub-micrometric spatial resolution. The aim of the current study is to investigate the microstructure and micro-damages of paired anatomical locations subjected to toughness experiments. We assessed the microstructure of human cortical bone of 8 paired radius diaphysis, femoral diaphysis and femoral necks (female, 50 - 91 y.o.) using Synchrotron Radiation (SR)-µCT in absorption and phase modes (voxel size of 0.7 µm). Image acquisition was performed on two different volumes of interest in each sample: the first one corresponds to a region where no particular mechanical stress was applied, in order to investigate structural differences between the locations; the second one, to a damaged region where three-point bending toughness tests were performed under a quasi-static strain rate (10-4 s-1), to evaluate structural changes, as micro-damages formation, due to crack propagation. Phase µCT allows the enhancement of the visibility of osteons, that might play a major role in crack propagation mechanisms as illustrated on Figure 1. After acquisition, we designed an image processing workflow to extract quantitative information on bone structural elements, such as Haversian canals, osteons or lacunae. Cracks and micro-damages were also segmented and quantified to investigate their relationships with human cortical bone toughness.