| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Borges, João Paulo Miranda Ribeiro
Universidade Nova de Lisboa
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (32/32 displayed)
- 2024Bioactive Hydroxyapatite Aerogels with Piezoelectric Particlescitations
- 2024Experimental study of Double-Elliptic-Ring-based thermomechanical metamaterials’ behaviourcitations
- 2023Biocomposite Macrospheres Based on Strontium-Bioactive Glass for Application as Bone Fillerscitations
- 2023Thermal, Structural, Morphological and Electrical Characterization of Cerium-Containing 45S5 for Metal Implant Coatingscitations
- 2023Extensive Investigation on the Effect of Niobium Insertion on the Physical and Biological Properties of 45S5 Bioactive Glass for Dental Implantcitations
- 2023Hydroxyapatite-Barium Titanate Biocoatings Using Room Temperature Coblastingcitations
- 2023Bioactive Glass Modified with Zirconium Incorporation for Dental Implant Applicationscitations
- 2022Characterization of a Biocomposite of Electrospun PVDF Membranes with Embedded BaTiO3 Micro- and Nanoparticlescitations
- 2020Conductive electrospun Polyaniline/Polyvinylpyrrolidone nanofibers: Electrical and morphological characterization of new yarns for electronic textilescitations
- 2019Using water to control electrospun Polycaprolactone fibre morphology for soft tissue engineeringcitations
- 2019Electrospun biodegradable chitosan based-poly(urethane urea) scaffolds for soft tissue engineeringcitations
- 2019Extraction of Cellulose Nanocrystals with Structure I and II and Their Applications for Reduction of Graphene Oxide and Nanocomposite Elaborationcitations
- 2019Development of polymeric anepectic meshes: Auxetic metamaterials with negative thermal expansioncitations
- 2019Polymer blending or fiber blending: a comparative study using chitosan and poly(ε-caprolactone) electrospun fiberscitations
- 2018Synthesis, electrospinning and in vitro test of a new biodegradable gelatin-based poly(ester urethane urea) for soft tissue engineeringcitations
- 2017Production of Electrospun Fast-Dissolving Drug Delivery Systems with Therapeutic Eutectic Systems Encapsulated in Gelatincitations
- 2017Tailoring the morphology of hydroxyapatite particles using a simple solvothermal routecitations
- 2017Hybrid polysaccharide-based systems for biomedical applicationscitations
- 2016Thermal and magnetic properties of chitosan-iron oxide nanoparticlescitations
- 2016Natural Nanofibres for Composite Applicationscitations
- 2016A simple sol-gel route to the construction of hydroxyapatite inverted colloidal crystals for bone tissue engineeringcitations
- 2015Osteogenisis enhancement of hydroxyapatite based materials by electrical polarization
- 2015Chitin-Based Nanocomposites: Biomedical Applicationscitations
- 2015Electrospun mats of biodegradable chitosan-based polyurethane urea
- 2015Antimicrobial electrospun silver-, copper-and zinc-doped polyvinylpyrrolidone nanofibers
- 2014Cellulose‐Based Liquid Crystalline Composite Systemscitations
- 2014Effects of surfactants on the magnetic properties of iron oxide colloidscitations
- 2014Electrical polarization of a chitosan-hydroxyapatite composite
- 2013Enhancing the Response of Chemocapacitors with Electrospun Nanofiber Filmscitations
- 2011All-Cellulosic Based Composites
- 2006Mechanical characterization of dense hydroxyapatite blockscitations
- 2001Cellulose-based composite filmscitations
Places of action
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article
Antimicrobial electrospun silver-, copper-and zinc-doped polyvinylpyrrolidone nanofibers
Abstract
Polyurethane ureas (PUU) are segmented polymers where soft and hard segments are separated in microphases. Usually, the soft segment is derived from a polyol and the hard segment from a diisocyanate and a chain extender. The PUU properties can be tuned in order to obtain biodegradable scaffolds with suitable mechanical properties for tissue engineering applications [1]. Electrospinning is a convenient technique for the production of nanofibrous scaffolds from a polymeric solution that mimic the extracellular matrix, thereby supporting cell attachment and growth [2]. The physico-chemical properties of the material used and the scaffold's architecture both provide cells with cues. In this work, we synthetized a PUU based on PCL-diol using CS as chain extender (PUU-CS) [3]. Molecular structure was analyzed by 1H NMR and FTIR. Thermogravimetric analysis was performed to examine the thermal stability. The PUU-CS was electrospun from solutions using a mixture of tetrahydrofuran and N, N-dimethylformamide as solvent. Randomly oriented and aligned fibres were collected on a static and on a rotating collector, respectively. Morphological properties were characterized by SEM and mechanical properties evaluated through tensile tests. Hydrolytic (phosphate buffer saline (PBS) solution) and enzymatic (lipase) degradation studies were carried out. The cytocompatibility of the PUU-CS fibre mats was evaluated using the extract method. A preliminary study of cell adhesion was also performed. Spectroscopic results confirmed that PUU-CS was successfully produced and is stable at least until 200 oC. Randomly oriented and aligned fibres with different mean diameters were obtained. Both types of fibre mats showed higher Young's modulus for the thinner fibres. Elongation at break was lower for the aligned fibre mats. No mass changes were observed in the mats during 3 months in PBS while significant degradation was observed in lipase. In vitro tests didn't demonstrate any toxicity of the extracts. Cells seeded on the mats were able to adhere. These properties make nanofiber mats based on PUU-CS good candidates for soft tissue engineering.