| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Mayer, Philipp
Technical University of Denmark
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (15/15 displayed)
- 2024Determining ecotoxicity drivers and biodegradation kinetics of discharged chemicals in produced water from oil and gas extraction in the North Sea
- 2018Assessing PCB pollution in the Baltic Sea - An equilibrium partitioning based studycitations
- 2018Headspace passive dosing for dose-response testing of volatile hydrophobic organic chemicals
- 2015Comparison of passive and standard dosing of polycyclic aromatic hydrocarbons to the marine algae Phaeodactylum tricornutum
- 2015Equilibrium passive sampling as a tool to study polycyclic aromatic hydrocarbons in Baltic Sea sediment pore-water systemscitations
- 2014The effect of humic acids on biodegradation of polycyclic aromatic hydrocarbons depends on the exposure regimecitations
- 2013Baseline Toxic Mixtures of Non-Toxic Chemicalscitations
- 2013The dosing determines mutagenicity of hydrophobic compounds in the Ames II assay with metabolic transformationcitations
- 2012Recreating the seawater mixture composition of HOCs in toxicity tests with Artemia franciscana by passive dosingcitations
- 2011A Contaminant Trap as a Tool for Isolating and Measuring the Desorption Resistant Fraction of Soil Pollutantscitations
- 2011Application of passive dosing to study the biotransformation and biodegradation of hydrophobic compounds
- 2011Application of passive dosing to study the biotransformation and biodegradation of hydrophobic
- 2010Controlling and maintaining exposure of hydrophobic organic compounds in aquatic toxicity tests by passive dosingcitations
- 2010Passive Dosing for Producing Defined and Constant Exposure of Hydrophobic Organic Compounds during in Vitro Toxicity Testscitations
- 2009In Situ Silicone Tube Microextractioncitations
Places of action
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document
Headspace passive dosing for dose-response testing of volatile hydrophobic organic chemicals
Abstract
Constant and well-defined exposure is crucial for the toxicity testing of liquid organic chemicals with high Henry’s constants, which are prone to substantial evaporative losses. A simple and effective headspace passive dosing method was developed and then applied to control the exposure of the freshwater algae Raphidocelis subcapitata and the terrestrial springtail Folsomia candida to terpenes and alkanes in toxicity experiments. The headspace passive dosing method applies a liquid partitioning donor placed in the headspace of the closed test vial for controlling exposure while avoiding direct contact and introduction of pure phase micro-droplets. Passive dosing from the pure liquid compound was applied for toxicity testing exactly at the solubility limit, and a dilution series of test chemicals prepared in purified vegetable oil served as donor for dose-response testing. The terpenes S-(-)-Limonene and a-(+)-Pinene were tested in both the algal growth inhibition test and the springtail test. In addition, n-nonane, n-undecane and n-tridecane were tested on the algae, while iso-octane, iso-dodecane and n-dodecane were tested on the springtails. Our first results demonstrated that (1) the headspace passive dosing method is a simple yet effective way to control exposure to volatile hydrophobic organic chemicals and (2) that the method is straightforward to apply in algal growth inhibition and springtail toxicity tests. Further analyses of exposure parameters are in progress to better understand and quantify the resulting toxicity.