| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Zhang, Jing
King's College London
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (11/11 displayed)
- 2024A Scalable Microfluidic Platform for Nanoparticle Formulation:For Exploratory- and Industrial-Level Scalescitations
- 2023Evaluating the clinical validity of genes related to hemostasis and thrombosis using the ClinGen gene curation frameworkcitations
- 2021Conventional Glass-ionomer Cements: A Guide for Practitionerscitations
- 2021Investigation of electrical properties of peald-deposited Ti/Al<sub>2</sub>O<sub>3</sub>/Al/Si MIM capacitorscitations
- 2021Super-resolved optical mapping of reactive sulfur-vacancy in 2D transition metal dichalcogenidescitations
- 2019In vitro compressive strength and edge stability testing of directly repaired glass-ionomer cementscitations
- 2018In-vitro subsurface remineralisation of artificial enamel white spot lesions pre-treated with chitosan
- 2018Remineralisation of enamel white spot lesions pre-treated with chitosan in the presence of salivary pelliclecitations
- 2016Efficient hydrogen evolution in transition metal dichalcogenides via a simple one-step hydrazine reactioncitations
- 2009Complexity of shear localization in a Zr-based bulk metallic glasscitations
- 2007Structural and Morphological Characterization of Cerium Oxide Nanocrystals Prepared by Hydrothermal Synthesiscitations
Places of action
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article
In-vitro subsurface remineralisation of artificial enamel white spot lesions pre-treated with chitosan
Abstract
Objective: to test the null hypothesis that chitosan application has no impact on the remineralisation of artificial incipient enamel white spot lesions (WSLs).<br/>Methods:66 artificial enamel WSLs were assigned to 6 experimental groups (n = 11): (1) bioactive glass slurry, (2) bioactive glass containing polyacrylic acid (BG+PAA) slurry, (3) chitosan pre-treated WSLs with BG slurry (CS-BG), (4) chitosan pre-treated WSLs with BG+PAA slurry (CS-BG+PAA), (5) remineralisation solution (RS) and (6) de-ionised water (negative control, NC). Surface and cross-sectional Raman intensity mapping (960 cm-1) were performed on 5 samples / group to assess mineral content. Raman spectroscopy and attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) were used to identify the type of newly formed minerals. Surface and cross-sectional Knoop microhardness were implemented to evaluate the mechanical properties after remineralisation. Surface morphologies and Ca/P ratio were observed using scanning electron microscopy (SEM) coupled with energy dispersive X-ray spectroscopy (EDX). Data were statistically analysed using one-way ANOVA with Tukey’s test.<br/>Results: BG+PAA, CS-BG, RS presented significantly higher mineral regain compared to NC on lesion surfaces, while CS-BG+PAA had higher subsurface mineral content. Newly mineralised crystals consist of type-B hydroxycarbonate apatite. CS-BG+PAA showed the greatest hardness recovery, followed by CS-BG, both significantly higher than other groups. SEM observations showed altered surface morphologies in all experimental groups except NC post-treatment. EDX suggested a higher content of carbon, oxygen and silicon in the precipitations in CS-BG+PAA group. There was no significant difference between each group in terms of Ca/P ratio.<br/>Conclusions: The null hypothesis was rejected. Chitosan pre-treatment enhanced WSL remineralisation with either BG only or with BG-PAA complexes. A further investigation using dynamic remineralisation/demineralisation system is required with regards to clinical application.<br/>