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Carregal-Romero, Ester
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document
Tunable full-field hollow and hybrid sol-gel photonic μtAS
Abstract
<p>A full-field generic photonic μTAS approach, which relies on functionalized hollow or bio-doped polymeric waveguides, is described. We show the potential of both full field configurations, where the transducer and the recognition elements are merged into one single microstructure. In contrast to evanescent field sensors, the sensor response does not only rely on the interaction of the evanescent wave with the recognition element, but on the interaction of the whole field, thus enabling a reduction of the sensor dimensions and/or a decrease of its limit of detection (LOD). The potential of this generic approach was demonstrated by developing a biosensor for the detection of H<sub>2</sub>O<sub>2</sub> using horseradish peroxidase (HRP) as the recognition element.</p>