| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Beeby, Steve
University of Southampton
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (45/45 displayed)
- 2024Synthesis and characterization of UV organic light-emitting electrochemical cells (OLECs) using phenanthrene fluorene derivatives for flexible applicationscitations
- 2023Vacuum thermoforming for packaging flexible electronics and sensors in e-textilescitations
- 2023Flexible thermoelectric fabrics based on self-assembled tellurium nanowires with a large power factor
- 2023A wearable all printed textile based 6.78 MHz 15 W output wireless power transfer system and it's screen printed joule heater applicationcitations
- 2022Screen-printed bismuth telluride nanostructured composites for flexible thermoelectric applicationscitations
- 2022Solution-processed organic light-emitting electrochemical cells (OLECs) with blue colour emission via silver-nanowires (AgNWs) as Cathode
- 2022Printable bifluorene based ultra-violet (UV) organic light-emitting electrochemical cells (OLECs) with improved device performancecitations
- 2021Visible and ultraviolet Light emitting electrochemical cells realised on woven textilescitations
- 2021Spray-coated organic light emitting electrochemical cells realized on a standard woven polyester cotton textilecitations
- 2021Spray-coated organic light emitting electrochemical cells realized on a standard woven polyester cotton textilecitations
- 2020Screen printed flexible water activated battery on woven cotton textile as a power supply for e-textile applicationscitations
- 2020Reliable UHF long-range textile-integrated RFID tag based on a compact flexible antenna filamentcitations
- 2020Spray coated light emitting electrochemical cells on standard polyester cotton woven textiles
- 2019Encapsulated textile organic solar cells fabricated by spray coatingcitations
- 2018CNTs-added PMNT/PDMS flexible piezoelectric nanocomposite for energy harvesting applicationcitations
- 2018CNTs-added PMNT/PDMS flexible piezoelectric nanocomposite for energy harvesting applicationcitations
- 2018Investigation of low temperature processed titanium dioxide (TiO2) films for printed dye sensitized solar cells (DSSCs) for large area flexible applicationscitations
- 2018Screen printed dye-sensitized solar cells (DSSCs) on woven polyester cotton fabric for wearable energy harvesting applicationscitations
- 2018Optimised process of fully spray-coated organic solar cells on woven polyester cotton fabricscitations
- 2018Energy-harvesting materials for smart fabrics and textilescitations
- 2018Solution processed organic solar cells on textilescitations
- 2017Flexible piezoelectric nano-composite films for kinetic energy harvesting from textilescitations
- 2016Fully spray-coated organic solar cells on woven polyester cotton fabrics for wearable energy harvesting applicationscitations
- 2015Clamping effect on the piezoelectric responses of screen-printed low temperature PZT/Polymer films on flexible substratescitations
- 2014Flexible screen printed thick film thermoelectric generator with reduced material resistivitycitations
- 2011HeLa cell transfection using a novel sonoporation systemcitations
- 2010Optimization of the electrodeposition process of high-performance bismuth antimony telluride compounds for thermoelectric applicationscitations
- 2009High density p-type Bi0.5Sb1.5Te3 nanowires by electrochemical templating through ion-track lithographycitations
- 2009High density p-type Bi0.5Sb1.5Te3 nanowires by electrochemical templating through ion-track lithographycitations
- 2009High density p-type Bi/sub 0.5/Sb/sub 1.5/Te/sub 3/ nanowires by electrochemical templating through ion-track lithography
- 2008Micro and nanotechnologies for thermoelectric generators
- 2008Performance improvement of a vibration-powered electromagnetic generator by reduced silicon surface roughnesscitations
- 2008Towards a nanostructured thermoelectric generator using ion-track lithographycitations
- 2008Development of nanostructures for thermoelectric microgenerators using ion-track lithographycitations
- 2007Nanostructured thermoelectric generator for energy harvesting
- 2007Microfluidic system for cell transfection using sonoporation and ultrasonic particle manipulation
- 2005An improved thick-film piezoelectric material by powder blending and enhanced processing parameters
- 2004Stiff Load Cell With High Overload Capability and Direct Frequency Output
- 2004Acoustic power output measurements for thick-film PZT transducerscitations
- 2004Improving the piezoelectric properties of thick-film PZTcitations
- 2004Development of metallic digital strain gauges
- 2003Screen Printed PZT Thick Films Using Composite Film Technology
- 2003A study of powder size combinations for improving piezoelectric properties of PZT thick-film devices
- 2002A study of the effect of powder preparation and milling process on the piezoelectric properties of thick-film PZT
- 2001Towards a piezoelectric vibration-powered microgeneratorcitations
Places of action
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document
Microfluidic system for cell transfection using sonoporation and ultrasonic particle manipulation
Abstract
Studies into sonoporation have grown rapidly in biotechnology and medicine in recent years. The use of sonoporation in biotechnology and medicine has potential for enhancing and targeting administration of drugs genes and other therapeutic compounds into the cells. Sonoporation has demonstrated to facilitate efficient gene transfer both in vitro and in vivo. This paper presents a microfluidic system for cells transfection using sonoporation and ultrasonic particle manipulation. The paper presents a theoretical analysis used to design the sonoporation chamber, whilst also enabling ultrasonic particle manipulation using an ultrasonic standing wave. Both the sonoporation and the particle manipulation are achieved using the same piezoelectric transducer (PZT 26) mounted on the micro chamber. The theoretical analysis is based on upon the model for an acoustic particle separator. The resulting design has been implemented in Macor ceramic glass assembly with a chamber size of 6 mm diameter and 750?m thickness. The efficiency of the sonoporation system was determined experimentally by the use of HeLa cells and propidium dye. The transfection rate was determined under a range of sonoporation conditions. The optimal sonoporation parameters will vary depending upon the cell type and purpose. For example, sonoporation typically utilises ultrasonic frequencies of 1 to 3MHz for gene delivery and drug delivery. The experiment results showed a peak cell transfection efficiency of 52.2% at 1.17MHz at 80 Vp-p.