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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Brucato, John Robert
Arcetri Astrophysical Observatory
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (7/7 displayed)
- 2022Phobos and Deimos surface composition: search for spectroscopic analoguescitations
- 2021Influence of the body composition on the evolution of ejecta in the Didymos-Dimorphos binary system
- 2021AstroBio CubeSat: operational design of a CubeSat for astrobiological purposes in radiative environment
- 2018Multi-Technique Analysis of "Synthetic" Extraterrestrial Analogs as Test-bed for Detection of Molecular Biomarkers in Planetary Contexts
- 2016Wild 2 grains characterized combining MIR/FIR/Raman micro-spectroscopy and FE-SEM/EDS analyses
- 2014Two refractory Wild 2 terminal particles from a carrot-shaped track characterized combining MIR/FIR/Raman microspectroscopy and FE-SEM/EDS analysescitations
- 2013Extraction Protocols for Life Marker Chip-Style Instruments
Places of action
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article
Extraction Protocols for Life Marker Chip-Style Instruments
Abstract
Extraction experiments were performed to evaluate suitable sample-extraction and processing protocols that will be used by bioanalytical instruments like Life Marker Chip (LMC), focused on the detection of molecules associated with life that will be extracted from the Martian soil. LMC is an antibody microarray biosensor instrument with optical readout, which uses fluorescent labels, analogous to the expected biomarkers, to detect and quantify the presence of polar and non-polar biomolecules, extracted from the Martian soil. The success of the LMC biomarkers detection experiment is dependent on the sample extraction protocol. The currently recommended extraction procedure, optimized for aliphatic biomarkers, consists in sonicating the samples using as solvent systemMeOH:H2O with surfactant, which respects all the tightening requirements associated to LMC biosensor. We have examined this procedure for a particular class of biomarkers, the nucleobases adenine, cytosine, uracil and hypoxanthine adsorbed onto martian analogues minerals.