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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Durrieu, Marie-Christine
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (6/6 displayed)
- 2024Silanization Strategies for Tailoring Peptide Functionalization on Silicon Surfaces: Implications for Enhancing Stem Cell Adhesioncitations
- 2019Remote imaging of single cell 3D morphology with ultrafast coherent phonons and their resonance harmonicscitations
- 2015Human mesenchymal stem cell behavior on femtosecond laser-textured Ti-6Al-4V surfacescitations
- 2015Probing single-cell mechanics with picosecond ultrasonicscitations
- 2014Chiral Colloids: Homogeneous Suspension of Individualized SiO2 Helical and Twisted Nanoribbons.citations
- 2007RGD nanodomains grafting onto titanium surface.
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article
RGD nanodomains grafting onto titanium surface.
Abstract
Titanium alloys exhibit excellent biocompatibility and corrosion resistance in the body fluid and possess mechanical properties similar of the bones' properties. When the loss of osseous is important in osseous surgery, large biomaterials are implanted and should be accepted by the organism. For increasing the biomaterials biocompatibility, biological compounds can be linked or deposited on the material surface making them biologically active. In order to study the tissue-implant interaction and to favor osteoblast-adhesion onto titanium, our work deals with the grafting of cell-binding peptides containing the Arginine-Glycine-Aspartic acid (RGD) sequence. In the present study, we focus on the elaboration of patterned biomaterial surfaces with highly functionalized nanodomains. The strategy of RGD peptide immobilization involves first the grafting if an amino-functional organosilane (APTES). Then, each of the free amino moieties were used as an initiator core for a dendrimer-like synthesis to multiply the number of free groups available for RGD immobilization on the material surface.