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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Liu, Wei
Universidad de Cantabria
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (20/20 displayed)
- 2024High Current Density Operation of a Proton Exchange Membrane Fuel Cell with Varying Inlet Relative Humidity—A Modeling Studycitations
- 2023Scalable manufacturing of quantum light emitters in silicon under rapid thermal annealingcitations
- 2023The effects of esketamine and treatment expectation in acute major depressive disorder (Expect): study protocol for a pharmacological fMRI study using a balanced placebo designcitations
- 2022Advanced Gene Therapy Strategies for the Repair of ACL Injuries
- 2020Free-Standing Graphene Oxide and Carbon Nanotube Hybrid Papers with Enhanced Electrical and Mechanical Performance and Their Synergy in Polymer Laminatescitations
- 2020Acceleration Factor Modeling of Flexible Electronic Substrates From Actual Human Body Measurements
- 2020Nanomechanics of graphene oxide-bacteriophage based self-assembled porous compositescitations
- 2020Free-standing graphene oxide and carbon nanotube hybrid papers with enhanced electrical and mechanic performance and their synergy in polymer laminatescitations
- 2018Self – supporting Hierarchical Porous PtAg Alloy Nanotubular Aerogels as Highly Active and Durable Electrocatalystscitations
- 2017Multimetallic Hierarchical Aerogels: Shape Engineering of the Building Blocks for Efficient Electrocatalysiscitations
- 2017Stealth Biocompatible Si-Based Nanoparticles for Biomedical Applicationscitations
- 2017Stealth Biocompatible Si-Based Nanoparticles for Biomedical Applicationscitations
- 2017Homogeneity and Elemental Distribution in Self-Assembled Bimetallic Pd-Pt Aerogels prepared by a spontaneous one-step gelation processcitations
- 2016Gold aerogels: Three-dimensional assembly of nanoparticles and their use as electrocatalytic interfacescitations
- 2016Identification of strain rate-dependent mechanical behaviour of DP600 under in-plane biaxial loadingscitations
- 2016Copolymerization of zinc-activated isoindigo- and naphthalene-diimide based monomers: an efficient route to low bandgap π-conjugated random copolymers with tunable properties
- 2016Strain Rate Dependent Hardening of DP600 Sheet Metal for Large Strains Under In-plane Biaxial Loadingscitations
- 2015Noble Metal Aerogels - Synthesis, Characterization, and Application as Electrocatalysts
- 2005[A case-control study on the mxA polymorphisms and susceptibility to severe acute respiratory syndromes].
- 2003[A case-control study on natural-resistance-associated macrophage protein 1 gene polymorphisms and susceptibility to pulmonary tuberculosis].
Places of action
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article
[A case-control study on natural-resistance-associated macrophage protein 1 gene polymorphisms and susceptibility to pulmonary tuberculosis].
Abstract
<h4>Objective</h4>To investigate association between the natural-resistance-associated macrophage protein 1 (NRAMP1) gene polymorphisms and susceptibility to pulmonary tuberculosis (TB) in Chinese Han population.<h4>Methods</h4>Hospital-based case-control study design was adopted. Polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) technique were used to type three NRAMP1 polymorphisms (INT4, D543N and 3'UTR). Information on related factors of tuberculosis was collected using a pre-tested standard questionnaire. Univariate and multivariate unconditional logistic analyses were conducted using SPSS for window software package. Totally, 110 cases of TB were selected during April 2001 to June 2002, with an average age of (27.7 +/- 12.7) years. Also, 180 cases of healthy control were selected, aged (27.3 +/- 9.2) years in average. Locus of NRAMP1 polymorphism was analysed with univariate method.<h4>Results</h4>Univariate analysis demonstrated that the D543N G/A and 3'UTR TGTG+/del genotype occurred more frequently in the cases than in the controls, with crude odds ratios (OR) (95% CI) of 2.22 (1.03 - 4.78) and 1.93 (1.14 - 3.26), respectively. No significant association was observed between TB and INT4 polymorphisms. In multivariate analysis, associations of TB and D543N G/A and 3'UTR TGTG+/del genotypes remained, adjusted for exposure history and bacille Camette-Guérin immunization. Adjusted OR (95% CI) was 3.04 (1.12 - 8.27) and 2.36 (1.20 - 4.64), respectively. Still, no significant association between INT4 polymorphisms and TB was found.<h4>Conclusion</h4>Polymorphisms of D543N and 3'UTR locus in NRAMP1 gene might affect their susceptibility to TB in Chinese Han population.