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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Lasgorceix, Marie
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (32/32 displayed)
- 20233D technology and antibacterial post-treatments: the process for the future manufacturing of bone substitutes?
- 2023Mg2+, Sr2+, Ag+, and Cu2+ co‐doped β‐tricalcium phosphate: Improved thermal stability and mechanical and biological propertiescitations
- 2023Fabrication of doped β-tricalcium phosphate bioceramics by Direct Ink Writing for bone repair applicationscitations
- 2023Synthesis and Direct Ink Writing of doped β-tricalcium phosphate bioceramics for bone repair applications
- 2023Shaping of complex ceramic parts by several additive manufacturing processes
- 2023Surface structuring of β-TCP and transition to α-TCP induced by femtosecond laser processingcitations
- 2023Macroporous biphasic calcium phosphate materials for bone substitute applications
- 2023Cold Sintering Process for developing hydroxyapatite ceramic and polymer composite
- 2023Cold Sintering Process for developing hydroxyapatite ceramic and polymer composite
- 20233D printing of doped β-tricalcium phosphate bioceramics using robocasting
- 2023Combination of indirect stereolithography and gel casting methods to shape ceramic dental crowns
- 2022Binder jetting process with ceramic powders ; Binder jetting process with ceramic powders: Influence of powder properties and printing parameterscitations
- 2022Shaping of complex ceramic parts using stereolithography and gel casting
- 2022Manufacturing methods of bioceramic scaffolds
- 2022Shaping of ceramics by hybrid binder jetting
- 2022Fabrication of doped β-tricalcium phosphate bioceramics by Direct Ink Writing for bone repair applicationscitations
- 2022Young Ceramists in the Spotlight
- 2022Shaping of ceramic by binder jetting
- 2022Fabrication of doped b-tricalcium phosphate bioceramics by robocasting for bone repair applications
- 2022Fabrication of doped b-tricalcium phosphate bioceramics by robocasting for bone repair applications
- 2022Post-infiltration to improve the density of binder jetting ceramic partscitations
- 2021Fabrication of higher thermal stability doped β-tricalcium phosphate bioceramics by robocasting
- 2021Influence of dopants on thermal stability and densification of β-tricalcium phosphate powderscitations
- 2021Development of calcium phosphate suspensions suitable for the stereolithography processcitations
- 2021Hybrid additive/subtractive manufacturing system to prepare dense and complicated ceramic parts
- 2020Fabrication of higher thermal stability doped β-tricalcium phosphate bioceramics by robocasting
- 2020Hybrid additive/subtractive manufacturing system to prepare dense and complex shape ceramic parts
- 2019Pre-osteoblast cell colonization of porous silicon substituted hydroxyapatite bioceramics: Influence of microporosity and macropore designcitations
- 2019Micropatterning of beta tricalcium phosphate bioceramic surfaces, by femtosecond laser, for bone marrow stem cells behavior assessmentcitations
- 2016Shaping by microstereolithography and sintering of macro–micro-porous silicon substituted hydroxyapatitecitations
- 2016Quantitative analysis of vascular colonisation and angio-conduction in porous silicon-substituted hydroxyapatite with various pore shapes in a chick chorioallantoic membrane (CAM) modelcitations
- 2014Shaping by microstereolithography and sintering of macro-micro-porous silicated hydroxyapatite ceramics and biological evaluation
Places of action
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conferencepaper
Synthesis and Direct Ink Writing of doped β-tricalcium phosphate bioceramics for bone repair applications
Abstract
Introduction β-tricalcium phosphate (β-TCP, β-Ca3(PO4)2) is one of the most attractive biomaterials for bone regeneration and β-TCP macroporous scaffolds are highly promising for bone tissue engineering. Direct Ink Writing (DIW), an additive manufacturing process based on the extrusion of a concentrated ceramic slurry, is particularly adapted to resolve the main drawbacks associated with conventional shaping of ceramic scaffolds. Methods In this work, undoped and co-doped β-TCP powders were synthetized by aqueous precipitation and used to print macroporous scaffolds by DIW. The doped compositions were produced combining magnesium, strontium, silver and copper cations: Mg-Sr (2.0–2.0 mol%) and Mg-Sr-Ag-Cu (2.0–2.0–0.1–0.1 mol%). DIW slurries were optimized with undoped and co-doped β-TCP with the use of a dispersant and a carboxymethylcellulose and polyethyleneimine mixture to obtain aqueous slurries filled with 42 vol% of powder. Undoped and co-doped β-TCP macroporous scaffolds were successfully printed by DIW and characterized. Results Doped β-TCP powders have been proved to exhibit higher thermal stability and densification compared to undoped β-TCP. The β-TCP slurries exhibited a shear-thinning and thixotropic behaviour suitable for the DIW process. The whole processing chain including printing, osmotic drying and sintering was optimized. Characterizations of the printed parts after sintering showed a reduction of macropores and microcracks using co-doped β-TCP powders as well as improved compressive strengths and densities compared to undoped β-TCP. Conclusion Improved compressive strength and densities were observed for co-doped β-TCP scaffolds with a significant enhancement by comparison with literature data. These results are encouraging for the development of on-demand customized bone substitutes applied to load-bearing areas. It was demonstrated that the developed process was successively applied to produce complex shapes, opening new possibilities for the fabrication of synthetic bone substitutes or other applications.