| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Choińska, Emilia
Warsaw University of Technology
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (16/16 displayed)
- 2024A comparative study of oxidation behavior of Co4Sb12 and Co4Sb10.8Se0.6Te0.6 skutterudite thermoelectric materials fabricated via fast SHS-PPS routecitations
- 20223D-Printed Drug Delivery Systems: The Effects of Drug Incorporation Methods on Their Release and Antibacterial Efficiency
- 2022The Utility of Recycled Rice Husk-Reinforced PVC Composite Profiles for Façade Claddingcitations
- 2021Biological and Corrosion Evaluation of In Situ Alloyed NiTi Fabricated through Laser Powder Bed Fusion (LPBF)citations
- 2021Plasma modification of carbon coating produced by RF CVD on oxidized NiTi shape memory alloy under glow-discharge conditionscitations
- 2020Molding Binder Influence on the Porosity and Gas Permeability of Ceramic Casting Moldscitations
- 2020The effect of diameter of fibre on formation of hydrogen bonds and mechanical properties of 3D-printed PCLcitations
- 2020The effect of introduction of filament shift on degradation behaviour of PLGA- and PLCL-based scaffolds fabricated via additive manufacturingcitations
- 2019Engineering Human-Scale Artificial Bone Grafts for Treating Critical-Size Bone Defectscitations
- 2018Nanobead-on-string composites for tendon tissue engineeringcitations
- 2018Micro and nanoscale characterization of poly(DL-lactic-co-glycolic acid) films subjected to the L929 cells and the cyclic mechanical loadcitations
- 2018Multi-scale characterization and biological evaluation of composite surface layers produced under glow discharge conditions on NiTi shape memory alloy for potential cardiological applicationcitations
- 2017Radiopaque biodegradable polymeric composites for in vivo monitoring of TE products by X-rays imaging
- 2016Increase of radiopacity of PCL scaffolds for their in vivo monitoring using x – rays imaging
- 2016Fabrication and characterization of electrospun bionanocomposites of poly (vinyl alcohol)/ nanohydroxyapatite/ cellulose nanofiberscitations
- 2013Investigations of polycaprolactone / gelatin blends in terms of their miscibilitycitations
Places of action
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document
Increase of radiopacity of PCL scaffolds for their in vivo monitoring using x – rays imaging
Abstract
INTRODUCTION: In vitro studies and mathematical modeling are very helpful in predicting behaviour of scaffolds after implantation. However, they cannot substitute in vivo monitoring. For this purpose, scaffolds should be visible in X-rays that enables to observe changes in morphology, detect cracks and defects, etc. [1] Contrast properties of polyesters can be improved by adding some radiopaque fillers. [2] The aim of the study was to investigate the influence of radiopaque filler barium sulfate (BaSO4) on widely used polycaprolactone–hydroxyapatite (PCL-HAp) composites.METHODS: Materials used in following experiments were prepared by solvent casting technique, dried in air at room temperature and then in a vacuum dryer. The compositions of prepared materials are presented in Table 1. Rods made of pure polymer and composites were fabricated by Fused Deposition Modeling (FDM) method and then incubated in phosphate-buffered saline (PBS). Calculations of mass loss and water absorption, micro computed tomography and cytotoxicity assay were used to characterise materials during degradation.RESULTS: The obtained composite rods had different image intensity. BaSO4 caused strong increase of visibility using X-rays but not increase of degradation rate of polymeric matrix. Additionally, higher content of HAp caused higher degradation rate and also increase of radiopaque properties of composite. There was no cytotoxic effect of using a BaSO4 as a filler in contact with murine fibroblast cell line L929.DISCUSSION & CONCLUSIONS: The concept of using a BaSO4 as a filler in scaffold material allows for a non-invasive approach for in vivo imaging. Absence of serious hazards in presence of BaSO4 was also observed in other works. [3,4] The results confirmed there is a possibility to obtain non-cytotoxic scaffold composition which enables monitoring of its stability after implantation in surrounding soft tissue, even in bone tissue.