| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Cook, Richard
University of Southampton
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (16/16 displayed)
- 2022Effect of chromium and molybdenum increment on the crystal structure, nanoindentation and corrosion properties of cobalt based alloyscitations
- 2022Measuring the elastic modulus of soft biomaterials using nanoindentationcitations
- 2020A comparative study on the physicochemical characteristics of nanoparticles released in vivo from CoCrMo tapers and cement-stem interfaces of total hip replacements
- 2019The effects of substrate dilution on the microstructure and wear resistance of PTA Cu-Al-Fe aluminium bronze coatingscitations
- 2018The effect of micro-abrasion on enamel using abrasive slurries
- 2018Defect-free TiC/Si multi-layer electrical discharge coatingscitations
- 2017Investigation of wear and corrosion products from around explanted CoCrMo tapers
- 2017Inside a feather
- 2016Influence of the manufacturing finishing on the nano-scale wear resistance at the taper-trunnion interface in hip implants
- 2016Nano-scale wear characterization of CoCrMo biomedical alloyscitations
- 2016The importance of the film structure during self-powered Ibuprofen salicylate drug release from polypyrrole electrodeposited on AZ31 Mgcitations
- 2015Sub-surface characterisation of tribological contact zone of metal hip prosthesescitations
- 2015Microstructure characterisation of hypereutectoid aluminium bronze composite coatingcitations
- 2014The effect of large-area pulsed electron beam melting on the corrosion and microstructure of a Ti6Al4V alloycitations
- 2013Pulsed electron beam surface melting of CoCrMo alloy for biomedical applicationscitations
- 2013Pseudotumour formation due to tribocorrosion at the taper interface of large diameter metal on polymer modular total hip replacementscitations
Places of action
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conferencepaper
Investigation of wear and corrosion products from around explanted CoCrMo tapers
Abstract
Metallic contacts in hip replacements are susceptible to wear and corrosion processes which lead to the release of particles and metal ions. Adverse local tissue reactions (ALTRs) and systemic manifestations to solid and soluble debris can be debilitating for the patients. It is believed that particles originating from CoCrMo taper junctions trigger more severe body reactions compared to debris from MoM hip bearings. The body’s reaction is highly dependent on particle characteristics, such as size, morphology, composition and aggregation state, which can reflect the specific wear and corrosion conditions at the site of release. Here we proposed to investigate wear and corrosion flakes collected from around CoCrMo tapers at the time of revision. The particles were initially characterised with scanning electron microscopy (SEM) and energy dispersive X-ray analysis (EDX). This revealed the microstructure of the corrosion products, which appeared to be made of smaller metallic aggregates, entrapped in a biological matrix. The in depth characterisation of the particles released from the organo-metallic composite, was performed with transmission electron microscopy (TEM) and scanning transmission electron microscopy (STEM), both fitted with EDX. The investigation revealed clusters and individual nanoparticles, as small as 3 nm, which represent the building blocks of the large corrosion flakes, reported and characterised in the past mainly with low resolution microscopy techniques. The majority of the particles consisted of Cr and O, potentially in the form of chromium oxides, with little evidence of Co and Mo. Particles size distribution (PSD) provided by STEM and TEM characterisation showed statistically different results. The STEM technique was able to resolve tiny particles found in close proximity and provided a PSD shift towards the smaller end of the size range.The study is the first to show microscopy evidence of Cr rich nanoparticles (3-60 nm) released in vivo from the modular taper interface, which can have important health implications caused by their increased potential to disseminate and corrode within the body.