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Costa, P. F.
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Topics
Publications (9/9 displayed)
- 2020Using 3D-printing to fabricate a microfluidic vascular model to mimic arterial thrombosis
- 2020Using 3D-printing to fabricate a microfluidic vascular model to mimic arterial thrombosis
- 2015Additively Manufactured Device for Dynamic Culture of Large Arrays of 3D Tissue Engineered Constructscitations
- 2014Automating the processing steps for obtaining bone tissue-engineered substitutes: From imaging tools to bioreactorscitations
- 2014Advanced tissue engineering scaffold design for regeneration of the complex hierarchical periodontal structurecitations
- 2014Biofabrication of customized bone grafts by combination of additive manufacturing and bioreactor knowhowcitations
- 2012Cryopreservation of cell/scaffold tissue-engineered constructscitations
- 2012All-in-one rapid-prototyped bioreactor/implant for semi-automated generation of tailor-made critical size bone tissue substitutes
- 2008A novel bioreactor design for enhanced stem cells proliferation and differentiation in tissue engineered constructs
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document
Using 3D-printing to fabricate a microfluidic vascular model to mimic arterial thrombosis
Abstract
<p>Vascular microfluidic models were manufactured using stereolithography and soft lithography based on computed tomography angiography data. These microfluidic chips were lined with endothelial cells and the devices could be perfused with human whole blood at arterial shear rates. When comparing healthy and stenotic geometries the healthy geometries showed no sign of platelet aggregation, while stenotic geometries showed platelet aggregation near and distal of the stenotic apex.</p>