• Zhou, Yi
• Leahy, Martin
• Nolan, Andrew
• Alexandrov, Sergey
• Chang, Ting-Chiao
• Dey, Rajib

Abstract

Python code to align multiple image segments taken of a glass wedge to create a full length wedge image. <br>This work is related to <br> Dey, R. <i>et al.</i> (2022) ‘Simple Characterization Scheme for Optical Coherence Tomography Systems With Application to a Commercial and a Near-Isometric Resolution Fibre-Based System’, <i>IEEE Photonics Journal</i>, 14(1), pp. 1–11. doi:10.1109/JPHOT.2021.3135058. <br>Abstract text:<br>Optical Coherence Tomography (OCT) is a rapidly growing imaging modality in biomedical optics. OCT can perform high-resolution, cross-sectional imaging of the microstructure of biological tissues by measuring the coherent spectrum from the backscattered light. OCT systems with broad spectral bandwidths are often constructed using free-space optics to avoid dispersion by fibre optic components. This paper presents a fibre-based OCT system with an axial resolution of 3.8m in air, surpassing any previously reported values to the best of our knowledge.<br>Despite the challenges in transporting a broadband spectrum using fibre-optics, the system investigation was motivated by the ever-increasing demand for commercialization of high-resolution OCT systems and simplification of construction. We also evaluate and demonstrate the direct measurement method for axial resolution using an air wedge. <br>Imaging of biomedical and other samples is demonstrated using a high numerical aperture sample lens and compared with images from a commercial OCT system. We discuss the effect of the improved structural visibility by achieving image voxels closer to an isometric shape with a high NA sample lens.<br>

Topics

• impedance spectroscopy
• dispersion
• tomography
• glass
• glass