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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Kellomäki, Minna
Tampere University of Technology
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (31/31 displayed)
- 2024A comprehensive study on rheological properties of photocrosslinkable gallol-metal complexed hyaluronic acid-based biomaterial inkscitations
- 2023Comprehensive characterisation of the compressive behaviour of hydrogels using a new modelling procedure and redefining compression testingcitations
- 2023Interpretable machine learning methods for monitoring polymer degradation in extrusion of polylactic acidcitations
- 2023Hydrolytic degradation of polylactide/polybutylene succinate blends with bioactive glasscitations
- 2023Chemical interactions in composites of gellan gum and bioactive glass: self-crosslinking and in vitro dissolutioncitations
- 2022Fractal-like Hierarchical CuO Nano/Microstructures for Large-Surface-to-Volume-Ratio Dip Catalystscitations
- 2022Injectable and self-healing biobased composite hydrogels as future anticancer therapeutic biomaterialscitations
- 2021Comprehensive characterisation of the compressive behaviour of hydrogels using a new modelling procedure and redefining compression testingcitations
- 2021Impact of glass composition on hydrolytic degradation of polylactide/bioactive glass compositescitations
- 2021In vitro degradation testing of hydrogels – concept and case study of gellan gum degradation in water
- 2020Evaluation of scaffold microstructure and comparison of cell seeding methods using micro-computed tomography-based toolscitations
- 2020Materials and Orthopedic Applications for Bioresorbable Inductively Coupled Resonance Sensorscitations
- 2020A tube-source X-ray microtomography approach for quantitative 3D microscopy of optically challenging cell-cultured samplescitations
- 2019Hydrolysis and drug release from poly(ethylene glycol)-modified lactone polymers with open porositycitations
- 2019Gas-foamed poly(lactide-co-glycolide) and poly(lactide-co-glycolide) with bioactive glass fibres demonstrate insufficient bone repair in lapine osteochondral defectscitations
- 2019Characterization of the microstructure of hydrazone crosslinked polysaccharide-based hydrogels through rheological and diffusion studiescitations
- 2019Characterization of the microstructure of hydrazone crosslinked polysaccharide-based hydrogels through rheological and diffusion studiescitations
- 2018Knitted 3D Scaffolds of Polybutylene Succinate Support Human Mesenchymal Stem Cell Growth and Osteogenesiscitations
- 2018Cell response to round and star-shaped polylactide fibers
- 2018Bioresorbable Conductive Wire with Minimal Metal Contentcitations
- 2017In vitro degradation of borosilicate bioactive glass and poly(L-lactide-co-ε-caprolactone) composite scaffoldscitations
- 2016Piezoelectric sensitivity of a layered film of chitosan and cellulose nanocrystalscitations
- 2016Inductively coupled passive resonance sensor for monitoring biodegradable polymers in vitrocitations
- 2016X-ray microtomography of collagen and polylactide samples in liquidscitations
- 2014Direct laser writing of synthetic poly(amino acid) hydrogels and poly(ethylene glycol) diacrylates by two-photon polymerizationcitations
- 2013Novel polypyrrole-coated polylactide scaffolds enhance adipose stem cell proliferation and early osteogenic differentiationcitations
- 2013An in vitro study of composites of poly(L-lactide-co-e-caprolactone), ß-tricalcium phosphate and ciprofloxacin intended for local treatment of osteomyelitiscitations
- 2012Processing and sustained in vitro release of rifampicin containing composites to enhance the treatment of osteomyelitiscitations
- 2011Knitted polylactide 96/4 L/D structures and scaffolds for tissue engineeringcitations
- 2011Investigation of the optimal processing parameters for picosecond laser-induced microfabrication of a polymer-ceramic hybrid materialcitations
- 2008Nano-, Pico- and femtosecond laser machining of bioabsorbable polymers and biomedical composites
Places of action
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article
Knitted polylactide 96/4 L/D structures and scaffolds for tissue engineering
Abstract
This study covers the whole production cycle, from biodegradable polymer processing to an in vivo tissue engineered construct. Six different biodegradable polylactide 96/4 L/D single jersey knits were manufactured using either four or eight multifilament fiber batches. The properties of those were studied in vitro for 42 weeks and in 0- to 3-year shelf life studies. Three types (Ø 12, 15 and 19 mm) of cylindrical scaffolds were manufactured from the knit, and the properties of those were studied in vitro for 48 weeks. For the Ø 15 mm scaffold type, mechanical properties were also studied in a one-year in vivo experiment. The scaffolds were implanted in the rat subcutis. All the scaffolds were g-irradiated prior to the studies. In vitro, all the knits lost 99% of their mechanical strength in 30 weeks. In the three-year follow up of shelf life properties, there was no decrease in the mechanical properties due to the storage time and only a 12% decrease in molecular weight. The in vitro and in vivo scaffolds lost their mechanical properties after 1 week. In the case of the in vivo samples, the mechanical properties were restored again, stepwise, by the presence of growing/maturing tissue between weeks 3 and 12. Faster degradation was observed with in vitro scaffolds compared to in vivo scaffolds during the one year follow up.