• Pereira, Luiz Carlos
• Alonso, Lizette Morejón
• Ribeiro, Alexandre Antunes
• Lunz, Juliana Do Nascimento
• Oliveira, Marize Varella De
• Cóta, Lívia Fernandes
• Licona, Karla Patricia Macedo

Abstract

<jats:p>Hydroxyapatite (HAp) has been synthesized by different techniques, and sonochemical methods have shown to be useful in the HAp nanopartcicles production for biomedical applications such as bone graft substitute. In addition, experimental design is an appropriate tool for planning and evaluating a study to meet specified objectives. Then, this work aimed to synthesize HAp nanosized powders by a sonochemical method and assess the processing parameters via experimental design, in order to obtain dense samples. HAp nanopowders were characterized by X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscope/Field Emission Gun (SEM/FEG). For densification analysis, HAp samples were processed with different parameters, such as: compaction pressure (200 or 400 MPa), sintering temperature (900 or 1100°C), sintering heating rate (2 or 20 °C/min), and sintering time (2 or 4 hours). The samples were analyzed by SEM/FEG, whereas the linear shrinkage and density were considered the response variables for the experimental design. The results indicated that the sonochemical method successfully produced HAp nanoparticles with sphere-like morphology. Further, the experimental design showed that sintering temperature was the variable that most influenced the densification of samples.</jats:p>

Topics

• nanoparticle
• density
• impedance spectroscopy
• scanning electron microscopy
• x-ray diffraction
• Fourier transform infrared spectroscopy
• sintering
• densification