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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Tighe, Brian J.
Aston University
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (21/21 displayed)
- 2024Low cytotoxicity, antibacterial property, and curcumin delivery performance of toughness-enhanced electrospun composite membranes based on poly(lactic acid) and MAX phase (Ti3AlC2)citations
- 2023In Situ Compatibilized Blends of PLA/PCL/CAB Melt-Blown Films with High Elongation: Investigation of Miscibility, Morphology, Crystallinity and Modellingcitations
- 2021The influence of structure and morphology on ion permeation in commercial silicone hydrogel contact lensescitations
- 2020Physical and thermal properties of l-lactide/ϵ-caprolactone copolymerscitations
- 2020Physical and thermal properties of l-lactide/ϵ-caprolactone copolymers:the role of microstructural design
- 2019Investigating the permeation properties of contact lenses and its influence on tear electrolyte compositioncitations
- 2018Biodegradable compatibilized poly(L-lactide)/thermoplastic polyurethane blends:design, preparation and property testing
- 2018Biodegradable compatibilized poly(L-lactide)/thermoplastic polyurethane blendscitations
- 2018Hydrophobic and Hydrophilic Effects on Water Structuring and Adhesion in Denture Adhesivescitations
- 2017Tuneable denture adhesives using biomimetic principles for enhanced tissue adhesion in moist environmentscitations
- 2016Bioplasticscitations
- 2016Structural design of contact lens-based drug delivery systems; in vitro and in vivo studies of ocular triggering mechanismscitations
- 2015Polymer-lipid interactionscitations
- 2014Controlled synthesis and processing of a poly(L-lactide-co-ε-caprolactone) copolymer for biomedical use as an absorbable monofilament surgical suturecitations
- 2014Identification of optically clear regions of ternary polymer blends using a novel rapid screening methodcitations
- 2012Charge-balanced copolymer hydrogels
- 2012Proteoglycan analogues for ophthalmic and orthopaedic applicationscitations
- 2011Adhesives and interfacial phenomena in wound healingcitations
- 2011Dehydration at the lens surface
- 2009Towards a synthetic osteo-odonto-keratoprosthesiscitations
- 2001Centrifugally-spun polyhydroxybutyrate fibres: Effect of process solvent on structure, morphology and cell responsecitations
Places of action
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article
Proteoglycan analogues for ophthalmic and orthopaedic applications
Abstract
The successful development of biomaterials is increasingly influenced by biomimesis essentially the use of biological structures as design templates. This approach has been used here in the design of injectable systems for the nucleus of the intervertebral disc, corneal inlays and intraocular lenses (IOLs). The strategy is based on the use of C-linked sulphonates to mimic the O-linked sulphate groups that are the hydration drivers in proteoglycans. The elastic modulus of the materials can be tailored for specific applications.