| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Yu, B.
Innovate UK
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2022Unconventional short-range structural fluctuations in cuprate superconductorscitations
- 2021Hygrothermal effects on the translaminar fracture toughness of a highly toughened aerospace CFRP: Experimental characterisation and model predictioncitations
- 2017Perforation resistance of CFRP beams to quasi-static and ballistic loading: The role of matrix strengthcitations
- 2017Perforation resistance of CFRP beams to quasi-static and ballistic loading: The role of matrix strength
- 2017Phosphate content affects structure and bioactivity of sol-gel silicate bioactive glassescitations
- 2016A comparison of different approaches for imaging cracks in composites by X-ray microtomographycitations
- 20152D and 3D imaging of fatigue failure mechanisms of 3D woven compositescitations
- 2015Evolution of damage during the fatigue of 3D woven glass-fibre reinforced composites subjected to tension-tension loading observed by time-lapse X-ray tomographycitations
- 2014Progressive fatigue damage in 3D modified layer-to-layer woven composites characterised by X-ray tomography
- 2013[Association of single nucleotide polymorphisms (SNPs) in leptin receptor gene with knee osteoarthritis in the Ningxia Hui population].citations
- 2012Bioactive silica-poly(γ-glutamic acid) hybrids for bone regeneration: Effect of covalent coupling on dissolution and mechanical properties and fabrication of porous scaffoldscitations
- 2012Luminescence and scintillation of Ce.sup.3+./sup.- doped high silica glasscitations
- 2011Luminescence and scintillation of Eu.sup.2+./sup.-doped high silica glasscitations
Places of action
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article
[Association of single nucleotide polymorphisms (SNPs) in leptin receptor gene with knee osteoarthritis in the Ningxia Hui population].
Abstract
To investigate the association between primary knee osteoarthritis (OA) and single nucleotide polymorphism (SNP) (A668G) of leptin receptor gene (LEPR) in the Ningxia Hui population. A case-control association study has been adopted in this thesis. The polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) analysis were performed to investigate the SNP of A668G site within LEPR from 148 patients with knee OA and 155 controls (asymptomatic and radiographically negative) with matched age and gender among Ningxia Hui population. In addition, genotypes of LEPR were verified by direct sequence analysis on PCR products. The result indicates that allele and genotype frequencies (P=0.024 and 0.008, respectively) in LEPR SNP A668G were significantly different in the knee OA patients group and control group, and in the knee OA patients group, the serum levels of leptin decreased significantly (P<0.001) and the serum levels of soluble leptin receptor increased significantly (P<0.001) compared with control group. Therefore, LEPR SNP A668G is associated with susceptibility to knee OA, which would be used as the genetic marker in predicting the risk of knee OA and would be one of the candidate genes in early prevention and control.