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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Devine, Declan
Irish Research Council
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (34/34 displayed)
- 2024Influence of Extrusion Screw Speed and CNT Concentration on the Mechanical and EMI Properties of PC/ABS Based Nanocompositescitations
- 2023Designing Sustainable Polymer Blendscitations
- 2023Investigation of Thermal, Mechanical and Shape Memory Properties of 3D-Printed Functionally Graded Nanocomposite Materialscitations
- 2023Effect of Mechanical Recycling on the Mechanical Properties of PLA-Based Natural Fiber-Reinforced Compositescitations
- 2023Rheological Behaviour of ABS/Metal Composites with Improved Thermal Conductivity for Additive Manufacturingcitations
- 2022Bioresorbable Chitosan-Based Bone Regeneration Scaffold Using Various Bioceramics and the Alteration of Photoinitiator Concentration in an Extended UV Photocrosslinking Reactioncitations
- 2022SMA-Based Haptic Gloves Usage in the Smart Factory Concept: XR Use Casecitations
- 2021Stereolithography (SLA) utilised to print injection mould tooling in order to evaluate thermal and mechanical properties of commercial polypropylenecitations
- 2021Physical properties of shellac material used for hot melt extrusion with potential application in the pharmaceutical industrycitations
- 2021Physical properties of shellac material used for hot melt extrusion with potential application in the pharmaceutical industry
- 2020Effect of stereolithography 3d printing on the properties of pegdma hydrogelscitations
- 2020Fused filament fabrication of peekcitations
- 2020Development of sustainable flexible packaging solutions using novel biodegradable and compostable polymer blends
- 2020Effect of stereolithography 3D printing on the properties of PEGDMA hydrogels.citations
- 2019Electrospun hydrogels composites for bone tissue engineering.
- 2019Comparison of fused-filament fabrication to direct compression and injection molding in the manufacture of oral tabletscitations
- 2019The production of a novel poly(vinyl alcohol) hydrogel cryogenic spheres for immediate release using a droplet systemcitations
- 2019Additive manufacturing of PLA/HNT nanocomposites for biomedical applicationscitations
- 2019Faster release of lumen-loaded drugs than matrix-loaded equivalent in polylactic acid/halloysite nanotubescitations
- 2019Photopolymerization for filling porous ceramic matrixcitations
- 20183D printed end of arm tooling (EOAT) of a robotic arm
- 2018Surface-modified halloysite nanotubes reinforced poly(lactic acid) for use in biodegradable coronary stentscitations
- 2018Material considerations for fused-filament fabrication of solid dosage formscitations
- 2018Electrospun hydrogels composites for bone tissue engineeringcitations
- 2018Degradable nanocomposites for fused filament fabrication applicationscitations
- 2017Halloysite nanotube reinforced polylactic acid compositecitations
- 2016Synthesis and characterization of high density polyethylene/peat ash compositescitations
- 2016Chemical surface modification of calcium carbonate particles with stearic acid using different treating methodscitations
- 2016Melt Extruded Bioresorbable Polymer Composites for Potential Regenerative Medicine Applicationscitations
- 2007Preparation of monolithic matrices for oral drug delivery using a supercritical fluid assisted hot melt extrusion processcitations
- 2007The incorporation of an organically modified layered silicate in monolithic polymeric matrices produced using hot melt extrusioncitations
- 2007The synthesis, swelling behaviour and rheological properties of chemically crosslinked thermosensitive copolymers based on N-isopropylacrylamidecitations
- 2006The use of Agar as a novel filler for monolithic matrices produced using hot melt extrusioncitations
- 2006Lower critical solution temperature control and swelling behaviour of physically crosslinked thermosensitive copolymers based on N-isopropylacrylamidecitations
Places of action
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article
Physical properties of shellac material used for hot melt extrusion with potential application in the pharmaceutical industry
Abstract
<p>Hot melt extrusion offers an efficient way of increasing the solubility of a poorly soluble drug. Shellac has potential as a pharmaceutical matrix polymer that can be used in this extrusion process, with further advantages for use in enteric drug delivery systems. The rheological property of a material affects the extrusion process conditions. However, the literature does not refer to any published work that investigates the processability of various shellac materials. This work explores various types of shellac and explores their physicochemical and thermal properties along with their processability in the hot melt extrusion application. Physicochemical characterization of the materials was achieved using differential scanning calorimetry, Fourier transform infrared spectroscopy, scanning electron microscopy and energy-dispersive X-ray spectroscopy. Additional processability characterization was achieved using melt flow index and rheology analysis. The results indicated that there was no chemical difference between the various shellac types compared in this study. However, the extrudable temperature ranges and rheological properties of different shellac types varied; SSB 55 Pharma FL had the lowest processing temperature and glass transition temperatures. Due to the shear-thinning behaviours, shellac can be extruded at lower temperatures. This study provides necessary data to determine the processing conditions in hot melt extrusion applications for the range of shellac materials.</p>