• Reis, Salette
• Lima, Sac

Abstract

<jats:p> Polymeric carriers play a key role in modern biomedical and nanomedicine applications. Polymers can be obtained from natural or synthetic sources and have been exploited given their chemistry to achieve interaction with living tissues and cells. Different types of carriers can be produced for drug delivery, namely, micelles, nanoparticles, dendrimers, sponges, hydrogels, and microneedles. With different coatings, appropriate adhesion and targeting features can be designed. Polymeric carriers allow the incorporation or conjugation of both hydrophilic and hydrophobic molecules and have tunable chemical and physical features that allow effective drug protection from degradation or denaturation. Other features are noteworthy in polymeric carriers, like their generally good biocompatibility and the ability to exhibit a slow and controlled dug release, allowing for the use in biomedical applications. [...]</jats:p>

Topics

• nanoparticle
• polymer
• dendrimer
• biocompatibility