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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Algarra, M.
Universidad Publica de Navarra
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (18/18 displayed)
- 2024Synergistic Enhancement of Targeted Wound Healing by Near-Infrared Photodynamic Therapy and Silver Metal–Organic Frameworks Combined with S- or N-Doped Carbon Dotscitations
- 2023Carbon Dots–TiO<sub>2</sub> Nanocomposites for the Enhanced Visible‐Light Driven Photodegradation of Methylene Bluecitations
- 2022Investigation of the role of pH and the stoichiometry of the N-dopant in the luminescence, composition and synthesis yield of carbon dotscitations
- 2017The Application of Functionalized Pillared Porous Phosphate Heterostructures for the Removal of Textile Dyes from Wastewatercitations
- 2016Characterization of cellulose membranes modified with luminescent silicon quantum dots nanoparticlescitations
- 2015ZnS:Mn nanoparticles functionalized by PAMAM-OH dendrimer based fluorescence ratiometric probe for cadmiumcitations
- 2014Fingerprint detection and using intercalated CdSe nanoparticles on non-porous surfacescitations
- 2013Solid luminescent CdSe-thiolated porous phosphate heterostructures. Application in fingermark detection in different surfacescitations
- 2013Inclusion of thiol DAB dendrimer/CdSe quantum dots based in a membrane structure: Surface and bulk membrane modificationcitations
- 2013Coal Rank Increase and Aerial Oxidation by a Combination of Fourier Transform Infrared Spectroscopy with Multivariate Analysiscitations
- 2012Thiolated DAB dendrimer/ZnSe nanoparticles for C-reactive protein recognition in human serumcitations
- 2012Thiolated DAB dendrimers and CdSe quantum dots nanocomposites for Cd(II) or Pb(II) sensingcitations
- 2011CdS nanocomposites assembled in porous phosphate heterostructures for fingerprint detectioncitations
- 2011Hybrid porous phosphate heterostructures as adsorbents of Hg(II) and Ni(II) from industrial sewagecitations
- 2011CdSe quantum dots capped PAMAM dendrimer nanocomposites for sensing nitroaromatic compoundscitations
- 2010Fluorescent Properties of a Hybrid Cadmium Sulfide-Dendrimer Nanocomposite and its Quenching with Nitromethanecitations
- 2010Porous phosphate heterostructures containing CdS quantum dots: assembly, characterization and photoluminescencecitations
- 2009Mercury(II) sensing based on the quenching of fluorescence of CdS-dendrimer nanocompositescitations
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article
Synergistic Enhancement of Targeted Wound Healing by Near-Infrared Photodynamic Therapy and Silver Metal–Organic Frameworks Combined with S- or N-Doped Carbon Dots
Abstract
<jats:p>The literature data emphasize that nanoparticles might improve the beneficial effects of near-infrared light (NIR) on wound healing. This study investigates the mechanisms of the synergistic wound healing potential of NIR light and silver metal–organic frameworks combined with nitrogen- and sulfur-doped carbon dots (AgMOFsN-CDs and AgMOFsS-CDs, respectively), which was conducted by testing the fibroblasts viability, scratch assays, biochemical analysis, and synchrotron-based Fourier transform infrared (SR-FTIR) cell spectroscopy and imaging. Our findings reveal that the combined treatment of AgMOFsN-CDs and NIR light significantly increases cell viability to nearly 150% and promotes cell proliferation, with reduced interleukin-1 levels, suggesting an anti-inflammatory response. SR-FTIR spectroscopy shows this combined treatment results in unique protein alterations, including increased α-helix structures and reduced cross-β. Additionally, protein synthesis was enhanced upon the combined treatment. The likely mechanism behind the observed changes is the charge-specific interaction of N-CDs from the AgMOFsN-CDs with proteins, enhanced by NIR light due to the nanocomposite’s optical characteristics. Remarkably, the complete wound closure in the in vitro scratch assay was achieved exclusively with the combined NIR and AgMOFsN-CDs treatment, demonstrating the promising application of combined AgMOFsN-CDs with NIR light photodynamic therapy in regenerative nanomedicine and tissue engineering.</jats:p>