| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Kriechbaum, Manfred
European Commission
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (16/16 displayed)
- 2023On The Multiscale Structure and Morphology of PVDF‐HFP@MOF Membranes in The Scope of Water Remediation Applicationscitations
- 2023On The Multiscale Structure and Morphology of PVDF-HFP@MOF Membranes in The Scope of Water Remediation Applicationscitations
- 2023Micelle Formation in Aqueous Solutions of the Cholesterol-Based Detergent Chobimalt Studied by Small-Angle Scattering
- 2023Poly(ethylene oxide)-block-poly(hexyl acrylate) Copolymers as Templates for Large Mesopore Sizes─A Detailed Porosity Analysiscitations
- 2023Lignin-Derived Mesoporous Carbon for Sodium-Ion Batteriescitations
- 2023The Nanostructured Self-Assembly and Thermoresponsiveness in Water of Amphiphilic Copolymers Carrying Oligoethylene Glycol and Polysiloxane Side Chainscitations
- 2023Synthesis and Characterization of Citric Acid-Modified Iron Oxide Nanoparticles Prepared with Electrohydraulic Discharge Treatmentcitations
- 2022Quantitative study on the face shear piezoelectricity and its relaxation in uniaxially-drawn and annealed poly-l-lactic acidcitations
- 2021Stable aqueous dispersions of bare and double layer functionalized superparamagnetic iron oxide nanoparticles for biomedical applicationscitations
- 2021Folic acid conjugation of magnetite nanoparticles using pulsed electrohydraulic dischargescitations
- 2020The Structural Integrity of the Model Lipid Membrane during Induced Lipid Peroxidationcitations
- 2018Synthesis and in vivo investigation of therapeutic effect of magnetite nanofluids in mouse prostate cancer model
- 2018High Hydrostatic Pressure Induces a Lipid Phase Transition and Molecular Rearrangements in Low-Density Lipoprotein Nanoparticlescitations
- 2018Mesostructure and physical properties of aqueous mixtures of the ionic liquid 1-ethyl-3-methyl imidazolium octyl sulfate doped with divalent sulfate salts in the liquid and the mesomorphic statescitations
- 2018Guerbet glycolipids from mannosecitations
- 2014Order vs. disorder — a huge increase in ionic conductivity of nanocrystalline LiAlO2 embedded in an amorphous-like matrix of lithium aluminatecitations
Places of action
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article
The Nanostructured Self-Assembly and Thermoresponsiveness in Water of Amphiphilic Copolymers Carrying Oligoethylene Glycol and Polysiloxane Side Chains
Abstract
<p>Amphiphilic copolymer self-assembly is a straightforward approach to obtain responsive micelles, nanoparticles, and vesicles that are particularly attractive for biomedicine, i.e., for the delivery of functional molecules. Here, amphiphilic copolymers of hydrophobic polysiloxane methacrylate and hydrophilic oligo (ethylene glycol) methyl ether methacrylate with different lengths of oxyethylenic side chains were synthesized via controlled RAFT radical polymerization and characterized both thermally and in solution. In particular, the thermoresponsive and self-assembling behavior of the water-soluble copolymers in water was investigated via complementary techniques such as light transmittance, dynamic light scattering (DLS), and small-angle X-ray scattering (SAXS) measurements. All the copolymers synthesized were thermoresponsive, displaying a cloud point temperature (T<sub>cp</sub>) strongly dependent on macromolecular parameters such as the length of the oligo(ethylene glycol) side chains and the content of the SiMA counits, as well as the concentration of the copolymer in water, which is consistent with a lower critical solution temperature (LCST)-type behavior. SAXS analysis revealed that the copolymers formed nanostructures in water below T<sub>cp</sub>, whose dimension and shape depended on the content of the hydrophobic components in the copolymer. The hydrodynamic diameter (D<sub>h</sub>) determined by DLS increased with the amount of SiMA and the associated morphology at higher SiMA contents was found to be pearl-necklace-micelle-like, composed of connected hydrophobic cores. These novel amphiphilic copolymers were able to modulate thermoresponsiveness in water in a wide range of temperatures, including the physiological temperature, as well as the dimension and shape of their nanostructured assemblies, simply by varying their chemical composition and the length of the hydrophilic side chains.</p>