| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Rodrigues, João
Universidade da Madeira
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (25/25 displayed)
- 2024Epidemiological and clinical trends of visceral leishmaniasis in Portugal: retrospective analysis of cases diagnosed in public hospitals between 2010 and 2020citations
- 2023Biological Effects in Cancer Cells of Mono- and Bidentate Conjugation of Cisplatin on PAMAM Dendrimers: A Comparative Studycitations
- 2023Experimental characterization of the nonlinear thermomechanical behaviour of refractory masonry with dry jointscitations
- 2023Target-Specific Delivery and Bioavailability of Pharmaceuticals via Janus and Dendrimer Particlescitations
- 2023Carbon dots and dendrimers nanohybrids: from synthesis to applicationscitations
- 2022Synthesis approach-dependent antiviral properties of silver nanoparticles and nanocompositescitations
- 2022New insights into ruthenium(ii) metallodendrimers as anticancer drug nanocarriers: from synthesis to preclinic behaviourcitations
- 2022Dendrimers and dendrimersomes as a novel tool for effective drug delivery applicationscitations
- 2022Strain-modulated optical response in 2D MoSe2 made by Na-assisted CVD on glasscitations
- 2021Use of Half-Generation PAMAM Dendrimers (G0.5-G3.5) with Carboxylate End-Groups to Improve the DACHPtCl(2) and 5-FU Efficacy as Anticancer Drugscitations
- 2021Efficient reSe2 photodetectors with CVD single-crystal graphene contactscitations
- 2021Cytocompatible cellulose nanofibers from invasive plant species Agave americana L. and Ricinus communis L.: a renewable green source of highly crystalline nanocellulosecitations
- 2020A Review on Thermoplastic or Thermosetting Polymeric Matrices Used in Polymeric Composites Manufactured with Banana Fibers from the Pseudostemcitations
- 2019Exploration of biomedical dendrimer space based on in-vivo physicochemical parameters: Key factor analysis (Part 2)citations
- 2018Mechanical Properties of Alumina Nanofilled Polymeric Composites Cured with DDSA and MNAcitations
- 2018Poly(alkylidenimine) Dendrimers Functionalized with the Organometallic Moiety [Ru(η5-C5H5)(PPh3)2]+ as Promising Drugs Against Cisplatin-Resistant Cancer Cells and Human Mesenchymal Stem Cellscitations
- 2018Recent therapeutic applications of the theranostic principle with dendrimers in oncologycitations
- 2017The influence of curing agents in the impact properties of epoxy resin nanocompositescitations
- 2016Effect of irregular shaped nanoalumina on the enhancement of mechanical properties of epoxy resin nanocomposites using DDM as hardenercitations
- 2015Octadecyl functionalized core-shell magnetic silica nanoparticle as a powerful nanocomposite sorbent to extract urinary volatile organic metabolitescitations
- 2015PAMAM Dendrimer/pDNA Functionalized-Magnetic Iron Oxide Nanoparticles for Gene Deliverycitations
- 2012The Effect of PAMAM Dendrimers on Mesenchymal Stem Cell Viability and Differentiationcitations
- 2012Injectable and biodegradable hydrogels: gelation, biodegradation and biomedical applicationscitations
- 2011ChemInform Abstract: Poly(alkylidenamines) Dendrimers as Scaffolds for the Preparation of Low‐Generation Ruthenium Based Metallodendrimers
- 2008Visible-light photolytic synthesis of multinuclear and dendritic iron-nitrile cationic complexes
Places of action
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document
Target-Specific Delivery and Bioavailability of Pharmaceuticals via Janus and Dendrimer Particles
Abstract
Nanosized Janus and dendrimer particles have emerged as promising nanocarriers for the target-specific delivery and improved bioavailability of pharmaceuticals. Janus particles, with two distinct regions exhibiting different physical and chemical properties, provide a unique platform for the simultaneous delivery of multiple drugs or tissue-specific targeting. Conversely, dendrimers are branched, nanoscale polymers with well-defined surface functionalities that can be designed for improved drug targeting and release. Both Janus particles and dendrimers have demonstrated their potential to improve the solubility and stability of poorly water-soluble drugs, increase the intracellular uptake of drugs, and reduce their toxicity by controlling the release rate. The surface functionalities of these nanocarriers can be tailored to specific targets, such as overexpressed receptors on cancer cells, leading to enhanced drug efficacy The design of these nanocarriers can be optimized by tuning the size, shape, and surface functionalities, among other parameters. The incorporation of Janus and dendrimer particles into composite materials to create hybrid systems for enhancing drug delivery, leveraging the unique properties and functionalities of both materials, can offer promising outcomes. Nanosized Janus and dendrimer particles hold great promise for the delivery and improved bioavailability of pharmaceuticals. Further research is required to optimize these nanocarriers and bring them to the clinical setting to treat various diseases. This article discusses various nanosized Janus and dendrimer particles for target-specific delivery and bioavailability of pharmaceuticals. In addition, the development of Janus-dendrimer hybrid nanoparticles to address some limitations of standalone nanosized Janus and dendrimer particles is discussed.