693.932 PEOPLE
| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Rantanen, Jukka
University of Copenhagen
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (43/43 displayed)
- 2024Leucine as a Moisture-Protective Excipient in Spray-Dried Protein/Trehalose Formulationcitations
- 2024Compaction behavior of freeze-dried and spray-dried trypsin/lactose particulate systems
- 2023Co-administration of Intravenous Drugscitations
- 2023Coating of Primary Powder Particles Improves the Quality of Binder Jetting 3D Printed Oral Solid Productscitations
- 2022Structured approach for designing drug-loaded solid products by binder jetting 3D printingcitations
- 2021Enabling formulations of aprepitantcitations
- 2020Fabrication of Mucoadhesive Buccal Films for Local Administration of Ketoprofen and Lidocaine Hydrochloride by Combining Fused Deposition Modeling and Inkjet Printingcitations
- 2020Exploring the Complexity of Processing-Induced Dehydration during Hot Melt Extrusion Using In-Line Raman Spectroscopycitations
- 2019Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparationcitations
- 2019Exploring the chemical space for freeze-drying excipientscitations
- 2019Roadmap to 3D printed oral pharmaceutical dosage formscitations
- 2018The use of molecular descriptors in the development of co-amorphous formulationscitations
- 2017Investigation of nanocarriers and excipients for preparation of nanoembedded microparticlescitations
- 2017Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozymecitations
- 2017The flow properties and presence of crystals in drug-polymer mixturescitations
- 2017The effect of poly (lactic-co-glycolic) acid composition on the mechanical properties of electrospun fibrous matscitations
- 2017The effect of poly (lactic-co-glycolic) acid composition on the mechanical properties of electrospun fibrous matscitations
- 2016Oscillatory Shear Rheology in Examining the Drug-Polymer Interactions Relevant in Hot Melt Extrusioncitations
- 2016Properties of the Sodium Naproxen-Lactose-Tetrahydrate Co-Crystal upon Processing and Storagecitations
- 2015Three-Dimensional Printing of Drug-Eluting Implantscitations
- 2015Well-plate freeze-dryingcitations
- 2015Rheology as a tool for evaluation of melt processability of innovative dosage formscitations
- 2014Evaluation of ring shear testing as a characterization method for powder flow in small-scale powder processing equipmentcitations
- 2014Near-Infrared Imaging for High-Throughput Screening of Moisture-Induced Changes in Freeze-Dried Formulationscitations
- 2013A step toward development of printable dosage forms for poorly soluble drugscitations
- 2013Interpreting the Disordered Crystal Structure of Sodium Naproxen Tetrahydratecitations
- 2013Designing CAF-adjuvanted dry powder vaccinescitations
- 2013Investigation of the phase separation of PNIPAM using infrared spectroscopy together with multivariate data analysiscitations
- 2013Fast-track to a solid dispersion formulation using multi-way analysis of complex interactionscitations
- 2013Foreign matter identification from solid dosage formscitations
- 2013Exploring the solid-form landscape of pharmaceutical hydratescitations
- 2012Complementing high-throughput X-ray powder diffraction data with quantum-chemical calculationscitations
- 2012Crystal morphology modification by the addition of tailor-made stereocontrolled poly(N-isopropyl acrylamide)citations
- 2012Atomic pairwise distribution function analysis of the amorphous phase prepared by different manufacturing routescitations
- 2011Assessment of crystalline disorder in cryo-milled samples of indomethacin using atomic pair-wise distribution functionscitations
- 2006Understanding processing-induced phase transformations in erythromycin-PEG 6000 solid dispersionscitations
- 2005Physical changes of beta-sitosterol crystals in oily suspensions during heatingcitations
- 2005IR spectroscopy together with multivariate data analysis as a process analytical tool for in-line monitoring of crystallization process and solid-state analysis of crystalline productcitations
- 2005Pellet manufacturing by extrusion-spheronization using process analytical technologycitations
- 2005Characterization of polymorphic solid-state changes using variable temperature X-ray powder diffractioncitations
- 2004Role of excipients in hydrate formation kinetics of theophylline in wet masses studied by near-infrared spectroscopycitations
- 2003Dehydration studies using a novel multichamber microscale fluid bed dryer with in-line near-infrared measurementcitations
- 2002Hydrate formation during wet granulation studied by spectroscopic methods and multivariate analysis
Places of action
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article
Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation
Abstract
Thermal conductivity is a material specific property, which influences many aspects of pharmaceutical development, such as processing, modelling, analysis, and the development of novel formulation approaches. We have presented a method to measure thermal conductivity of small molecule organic glasses, based on a vacuum molding sample preparation technique combined with modulated differential scanning calorimetry. The method is applied to the two amorphous model compounds indomethacin and celecoxib. The measured values of below 0.2 W/m °C indicate very low thermal conductivity of the amorphous compounds, within the range of organic liquids and low conducting polymers.