Materials Map

Discover the materials research landscape. Find experts, partners, networks.

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The Materials Map is an open tool for improving networking and interdisciplinary exchange within materials research. It enables cross-database search for cooperation and network partners and discovering of the research landscape.

The dashboard provides detailed information about the selected scientist, e.g. publications. The dashboard can be filtered and shows the relationship to co-authors in different diagrams. In addition, a link is provided to find contact information.

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The Materials Map is still under development. In its current state, it is only based on one single data source and, thus, incomplete and contains duplicates. We are working on incorporating new open data sources like ORCID to improve the quality and the timeliness of our data. We will update Materials Map as soon as possible and kindly ask for your patience.

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in Cooperation with on an Cooperation-Score of 37%

Topics

Publications (6/6 displayed)

  • 2023Complexation between the Antioxidant Pterostilbene and Derivatized Cyclodextrins in the Solid State and in Aqueous Solution4citations
  • 2021Shape fidelity and sterility assessment of 3D printed polycaprolactone and hydroxyapatite scaffolds8citations
  • 2014In-Solution Structural Considerations by1H NMR and Solid-State Thermal Properties of Inulin-d-α-Tocopherol Succinate (INVITE) Micelles as Drug Delivery Systems for Hydrophobic Drugs28citations
  • 2013Effect of micelles formation and drug loading on thermal properties of Inulin-graft- Vitamin E (INVITE) polymerscitations
  • 2011Albumin nanoparticles carrying cyclodextrins for nasal deliveryof the anti-Alzheimer drug tacrinecitations
  • 2010Thermal characterization of diltiazem and lamba-carrageenan binary systems5citations

Places of action

Chart of shared publication
Bonferoni, Maria Cristina
2 / 9 shared
Sorrenti, Milena Lillina
5 / 5 shared
Sorrenti, Milena
1 / 3 shared
Conti, Michele
1 / 4 shared
Marconi, Stefania
1 / 6 shared
Scocozza, Franca
1 / 1 shared
Scatto, Marco
1 / 6 shared
Sakaj, Mirena
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Ferrari, Cinzia
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Riello, Pietro
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Auricchio, Ferdinando
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Cansolino, Laura
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Colombo, Lino
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Tripodo, Giuseppe
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Mandracchia, Delia
1 / 1 shared
Serra, Massimo
1 / 1 shared
Mandracchia, D.
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Delucca, Alice
1 / 1 shared
Bigucci, Federica
1 / 1 shared
Cerchiara, Teresa
1 / 1 shared
Pietra, Anna Maria Di
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Corace, Giuseppe
1 / 1 shared
Luppi, Barbara
1 / 1 shared
Zecchi, Vittorio
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Sandri, Giuseppina
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Bettinetti, Giampiero
1 / 1 shared
Caramella, Carla Marcella
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Chart of publication period
2023
2021
2014
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2011
2010

Co-Authors (by relevance)

  • Bonferoni, Maria Cristina
  • Sorrenti, Milena Lillina
  • Sorrenti, Milena
  • Conti, Michele
  • Marconi, Stefania
  • Scocozza, Franca
  • Scatto, Marco
  • Sakaj, Mirena
  • Ferrari, Cinzia
  • Riello, Pietro
  • Auricchio, Ferdinando
  • Cansolino, Laura
  • Colombo, Lino
  • Tripodo, Giuseppe
  • Mandracchia, Delia
  • Serra, Massimo
  • Mandracchia, D.
  • Delucca, Alice
  • Bigucci, Federica
  • Cerchiara, Teresa
  • Pietra, Anna Maria Di
  • Corace, Giuseppe
  • Luppi, Barbara
  • Zecchi, Vittorio
  • Sandri, Giuseppina
  • Bettinetti, Giampiero
  • Caramella, Carla Marcella
OrganizationsLocationPeople

article

Complexation between the Antioxidant Pterostilbene and Derivatized Cyclodextrins in the Solid State and in Aqueous Solution

  • Bonferoni, Maria Cristina
  • Catenacci, Laura
  • Sorrenti, Milena Lillina
Abstract

<jats:p>Inadequate aqueous solubilities of bioactive compounds hinder their ability to be developed for medicinal applications. The potent antioxidant pterostilbene (PTB) is a case in point. The aim of this study was to use a series of modified water-soluble cyclodextrins (CDs), namely, hydroxypropyl β-CD (HPβCD), dimethylated β-CD (DIMEB), randomly methylated β-CD (RAMEB), and sulfobutyl ether β-CD sodium salt (SBECD) to prepare inclusion complexes of PTB via various solid, semi-solid, and solution-based treatments. Putative CD–PTB products generated by solid-state co-grinding, kneading, irradiation with microwaves, and the evaporative treatment of CD–PTB solutions were considered to have potential for future applications. Primary analytical methods for examining CD–PTB products included differential scanning calorimetry and Fourier transform infrared spectroscopy to detect the occurrence of binary complex formation. Phase solubility analysis was used to probe CD–PTB complexation in an aqueous solution. Complexation was evident in both the solid-state and in solution. Complex association constants (K1:1) in an aqueous solution spanned the approximate range of 15,000 to 55,000 M−1; the values increased with the CDs in the order HPβCD &lt; DIMEB &lt; RAMEB &lt; SBECD. Significant PTB solubility enhancement factors were recorded at 100 mM CD concentrations, the most accurately determined values being in the range 700-fold to 1250-fold.</jats:p>

Topics
  • impedance spectroscopy
  • compound
  • inclusion
  • phase
  • grinding
  • Sodium
  • differential scanning calorimetry
  • Fourier transform infrared spectroscopy