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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Ribeiro, Clarisse
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (32/32 displayed)
- 2023Development of Silk Fibroin Scaffolds for Vascular Repaircitations
- 2023Natural Indigenous Paper Substrates for Colorimetric Bioassays in Portable Analytical Systems: Sustainable Solutions from the Rain Forests to the Great Plainscitations
- 2023Graphene Based Printable Conductive Wax for Low‐Power Thermal Actuation in Microfluidic Paper‐Based Analytical Devicescitations
- 2023Enhanced neuronal differentiation by dynamic piezoelectric stimulationcitations
- 2022Electrospun Magnetic Ionic Liquid Based Electroactive Materials for Tissue Engineering Applicationscitations
- 2022Piezoelectric and Magnetically Responsive Biodegradable Composites with Tailored Porous Morphology for Biotechnological Applicationscitations
- 2022Environmentally friendly conductive screen‐printable inks based on N‐Doped graphene and polyvinylpyrrolidonecitations
- 2022Understanding Myoblast Differentiation Pathways When Cultured on Electroactive Scaffolds through Proteomic Analysiscitations
- 2022Printed multifunctional magnetically activated energy harvester with sensing capabilitiescitations
- 2022Tuning magnetic response and ionic conductivity of electrospun hybrid membranes for tissue regeneration strategiescitations
- 2021Ionic Liquid-Based Materials for Biomedical Applicationscitations
- 2020Patterned Piezoelectric Scaffolds for Osteogenic Differentiationcitations
- 2020Morphology dependence degradation of electro-and magnetoactive poly(3-hydroxybutyrateco-hydroxyvalerate) for tissue engineering applicationscitations
- 2020Silica nanoparticles surface charge modulation of the electroactive phase content and physical-chemical properties of poly(vinylidene fluoride) nanocompositescitations
- 2020Magnetic Bioreactor for Magneto-, Mechano- and Electroactive Tissue Engineering Strategiescitations
- 2020Biodegradable Hydrogels Loaded with Magnetically Responsive Microspheres as 2D and 3D Scaffoldscitations
- 2020Morphology Dependence Degradation of Electro- and Magnetoactive Poly(3-hydroxybutyrate-co-hydroxyvalerate) for Tissue Engineering Applicationscitations
- 2019Development of bio-hybrid piezoresistive nanocomposites using silk-elastin protein copolymerscitations
- 2019Ionic-liquid-based electroactive polymer composites for muscle tissue engineeringcitations
- 2018Tailored biodegradable and electroactive poly(hydroxybutyrate-co-hydroxyvalerate) based morphologies for tissue engineering applicationscitations
- 2018Electroactive poly(vinylidene fluoride)-based structures for advanced applicationscitations
- 2018Multifunctional platform based on electroactive polymers and silica nanoparticles for tissue engineering applicationscitations
- 2018Silk fibroin-magnetic hybrid composite electrospun fibers for tissue engineering applicationscitations
- 2018Electroactive biomaterial surface engineering effects on muscle cells differentiationcitations
- 2018Relation between fiber orientation and mechanical properties of nano-engineered poly(vinylidene fluoride) electrospun composite fiber matscitations
- 2018Fluorinated polymers as smart materials for advanced biomedical applicationscitations
- 2018Tailored Biodegradable and Electroactive Poly(Hydroxybutyrate-Co-Hydroxyvalerate) Based Morphologies for Tissue Engineering Applicationscitations
- 2017Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applicationscitations
- 2016Electromechanical actuators based on poly(vinylidene fluoride) with [N1 1 1 2(OH)][NTf2] and [C2mim] [C2SO4]citations
- 2016Development of poly(vinylidene fluoride)/ionic liquid electrospun fibers for tissue engineering applicationscitations
- 2015Influence of oxygen plasma treatment parameters on poly(vinylidene fluoride) electrospun fiber mats wettabilitycitations
- 2015Piezoelectric polymers as biomaterials for tissue engineering applicationscitations
Places of action
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article
Multifunctional platform based on electroactive polymers and silica nanoparticles for tissue engineering applications
Abstract
Poly(vinylidene fluoride) nanocomposites processed with different morphologies, such as porous and non-porous films and fibres, have been prepared with silica nanoparticles (SiNPs) of varying diameter (17, 100, 160 and 300 nm), which in turn have encapsulated perylenediimide (PDI), a fluorescent molecule. The structural, morphological, optical, thermal, and mechanical properties of the nanocomposites, with SiNP filler concentration up to 16 wt %, were evaluated. Furthermore, cytotoxicity and cell proliferation studies were performed. All SiNPs are negatively charged independently of the pH and more stable from pH 5 upwards. The introduction of SiNPs within the polymer matrix increases the contact angle independently of the nanoparticle diameter. Moreover, the smallest ones (17 nm) also improve the PVDF Youngs modulus. The filler diameter, physico-chemical, thermal and mechanical properties of the polymer matrix were not significantly affected. Finally, the SiNPs inclusion does not induce cytotoxicity in murine myoblasts (C2C12) after 72 h of contact and proliferation studies reveal that the prepared composites represent a suitable platform for tissue engineering applications, as they allow us to combine the biocompatibility and piezoelectricity of the polymer with the possible functionalization and drug encapsulation and release of the SiNP. ; This work was supported by the Portuguese Foundation for Science and Technology (FCT) in the framework of the Strategic Funding UID/FIS/04650/2013 and UID/BIA/04050/2013 (POCI-01-0145-FEDER-007569) and project POCI-01-0145-FEDER-028237 funded by national funds through Fundação para a Ciência e a Tecnologia (FCT) and by the ERDF through the COMPETE2020-Programa Operacional Competitividade e Internacionalização (POCI); and also under the scope of the strategic funding of UID/BIO/04469 unit and COMPETE 2020 (POCI-01-0145-FEDER-006684) and BioTecNorte operation (NORTE-01-0145-FEDER-000004) funded by the European Regional Development Fund under the scope of Norte2020-Programa ...