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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Popov, Alexey
VTT Technical Research Centre of Finland
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2024SnS2 Thin Film with In Situ and Controllable Sb Doping via Atomic Layer Deposition for Optoelectronic Applicationscitations
- 2021From Cyclopentasilane to Thin‐Film Transistorscitations
- 2021Dimethylammonium iodide stabilized bismuth halide perovskite photocatalyst for hydrogen evolutioncitations
- 2018Markers of Oxidative Stress in the Exhaled Breath Condensate of Workers Handling Nanocompositescitations
- 2018Partial magnetic ordering in one-dimensional arrays of endofullerene single-molecule magnet peapodscitations
- 2018Deep Airway Inflammation and Respiratory Disorders in Nanocomposite Workerscitations
- 2017Polycyclic heteroaromatic hydrocarbons containing a benzoisoindole corecitations
- 2014Titania nanofibers in gypsum compositescitations
- 2014Gold nanostructures for OCT imaging of capillary flowcitations
- 2013Growth of all-carbon horizontally aligned single-walled carbon nanotubes nucleated from fullerene-based structurescitations
- 2013Plasmon-resonant gold nanoparticles with variable morphology as optical labels and drug carriers for cytological researchcitations
- 2012Understanding High-Yield Catalyst-Free Growth of Horizontally Aligned Single-Walled Carbon Nanotubes Nucleated by Activated C <sub>60</sub> Speciescitations
- 2011Growth of catalyst-assisted and catalyst-free horizontally aligned single wall carbon nanotubescitations
Places of action
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article
Markers of Oxidative Stress in the Exhaled Breath Condensate of Workers Handling Nanocomposites
Abstract
<jats:p>Researchers in nanocomposite processing may inhale a variety of chemical agents, including nanoparticles. This study investigated airway oxidative stress status in the exhaled breath condensate (EBC). Nineteen employees (42.4 ± 11.4 y/o), working in nanocomposites research for 18.0 ± 10.3 years were examined pre-shift and post-shift on a random workday, together with nineteen controls (45.5 ± 11.7 y/o). Panels of oxidative stress biomarkers derived from lipids, nucleic acids, and proteins were analyzed in the EBC. Aerosol exposures were monitored during three major nanoparticle generation operations: smelting and welding (workshop 1) and nanocomposite machining (workshop 2) using a suite of real-time and integrated instruments. Mass concentrations during these operations were 0.120, 1.840, and 0.804 mg/m3, respectively. Median particle number concentrations were 4.8 × 104, 1.3 × 105, and 5.4 × 105 particles/cm3, respectively. Nanoparticles accounted for 95, 40, and 61%, respectively, with prevailing Fe and Mn. All markers of nucleic acid and protein oxidation, malondialdehyde, and aldehydes C6–C13 were elevated, already in the pre-shift samples relative to controls in both workshops. Significant post-shift elevations were documented in lipid oxidation markers. Significant associations were found between working in nanocomposite synthesis and EBC biomarkers. More research is needed to understand the contribution of nanoparticles from nanocomposite processing in inducing oxidative stress, relative to other co-exposures generated during welding, smelting, and secondary oxidation processes, in these workshops.</jats:p>