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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Khan, Imran
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (18/18 displayed)
- 2023The impact of plasmonic electrodes on the photocarrier extraction of inverted organic bulk heterojunction solar cellscitations
- 2023The impact of plasmonic electrodes on the photocarrier extraction of inverted organic bulk heterojunction solar cells
- 2023Dodecyltrimethylammonium bromide-styrene microemulsion dielectric investigation in aqueous media
- 2022Biogenic Synthesis of Silver Nanoparticles Using Catharanthus roseus and Its Cytotoxicity Effect on Vero Cell Linescitations
- 2021Correlation between the microstructure and corrosion performance of the HIPIMS nitrided bio-grade CoCrMo alloycitations
- 2021Development of Cd (II) Ion Probe Based on Novel Polyaniline-Multiwalled Carbon Nanotube-3-aminopropyltriethoxylsilane Compositecitations
- 2021A new approach towards performing plasma nitriding of CrCoMo medical grade alloys using HIPIMS dischargecitations
- 2021Efficient Synthesis and Characterization of Polyaniline@Aluminium–Succinate Metal-Organic Frameworks Nanocomposite and Its Application for Zn(II) Ion Sensingcitations
- 2021TiN/NbN nanoscale multilayer coatings deposited by High Power Impulse Magnetron Sputtering to protect medical grade CoCrMo alloyscitations
- 2021TiN/NbN Nanoscale Multilayer Coatings Deposited by High Power Impulse Magnetron Sputtering to Protect Medical-Grade CoCrMo Alloyscitations
- 2020Dry sliding wear mechanisms of HIPIMS plasma nitrided CoCrMo alloy for medical implant applicationscitations
- 2020Surface plasmon resonance excited electron induction greatly extends H<sub>2</sub> evolution and pollutant degradation activity of g‐C<sub>3</sub>N<sub>4</sub> under visible light irradiationcitations
- 2020Low pressure plasma nitrided CoCrMo alloy utilising HIPIMS discharge for biomedical applicationscitations
- 2020Effect of Nitriding Voltage on the Impact Load Fatigue and Fracture Toughness Behaviour of CoCrMo Alloy Nitrided Utilising a HIPIMS Dischargecitations
- 2020Investigation on the effects of the processing parameters and the number of passes on the flexural properties of polymer nanocomposite fabricated through FSP method
- 2019The exploitation of polymer based nanocomposites for additive manufacturing: a prospective reviewcitations
- 2018Rubber-Based Nanocomposites and Significance of Ionic Liquids in Packaging Applications
- 2016Development of superlattice CrNNbN coatings for joint replacements deposited by High Power Impulse Magnetron Sputteringcitations
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article
Biogenic Synthesis of Silver Nanoparticles Using Catharanthus roseus and Its Cytotoxicity Effect on Vero Cell Lines
Abstract
<jats:p>Background: Type 2 diabetes mellitus (DM2) is a chronic and sometimes fatal condition which affects people all over the world. Nanotherapeutics have shown tremendous potential to combat chronic diseases—including DM2—as they enhance the overall impact of drugs on biological systems. Greenly synthesized silver nanoparticles (AgNPs) from Catharanthus roseus methanolic extract (C. AgNPs) were examined primarily for their cytotoxic and antidiabetic effects. Methods: Characterization of C. AgNPs was performed by UV–vis spectroscopy, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and atomic force microscopy (AFM). The C. AgNPs were trialed on Vero cell line and afterwards on an animal model (rats). Results: The C. AgNPs showed standard structural and functional characterization as revealed by FTIR and XRD analyses. The zetapotential analysis indicated stability while EDX analysis confirmed the formation of composite capping with Ag metal. The cytotoxic effect (IC50) of C. AgNPs on Vero cell lines was found to be 568 g/mL. The animal model analyses further revealed a significant difference in water intake, food intake, body weight, urine volume, and urine sugar of tested rats after treatment with aqueous extract of C. AgNPs. Moreover, five groups of rats including control and diabetic groups (NC1, PC2, DG1, DG2, and DG3) were investigated for their blood glucose and glycemic control analysis. Conclusions: The C. AgNPs exhibited positive potential on the Vero cell line as well as on experimental rats. The lipid profile in all the diabetic groups (DG1-3) were significantly increased compared with both of the control groups (p < 0.05). The present study revealed the significance of C. AgNPs in nanotherapeutics.</jats:p>