| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Wysocki, Bartłomiej
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (14/14 displayed)
- 2022How to Control the Crystallization of Metallic Glasses During Laser Powder Bed Fusion? Towards Part-Specific 3d Printing of in Situ Composites
- 2020Analysis of Microstructure and Properties of a Ti–AlN Composite Produced by Selective Laser Meltingcitations
- 2019The influence of chemical polishing of titanium scaffolds on their mechanical strength and in-vitro cell responsecitations
- 2019New approach to amorphization of alloys with low glass forming ability via selective laser meltingcitations
- 2018The Influence of Selective Laser Melting (SLM) Process Parameters on In-Vitro Cell Responsecitations
- 2018Investigation of the relationship between morphology and permeability for open-cell foams using virtual materials testingcitations
- 2018Structure and porosity of titanium scaffolds manufactured by selective laser meltingcitations
- 2017Microstructure and mechanical properties investigation of CP titanium processed by selective laser melting (SLM)citations
- 2017Fabrication of custom designed spinal disc replacement for veterinary applications
- 2017Laser and Electron Beam Additive Manufacturing Methods of Fabricating Titanium Bone Implantscitations
- 2016The process of design and manufacturing of titanium scaffolds in the SLM technology for tissue engineering
- 2016Post Processing and Biological Evaluation of the Titanium Scaffolds for Bone Tissue Engineeringcitations
- 2016The Novel Scanning Strategy For Fabrication Metallic Glasses By Selective Laser Melting
- 2015CNTs as ion carriers in formation of calcium phosphate coatingscitations
Places of action
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article
Post Processing and Biological Evaluation of the Titanium Scaffolds for Bone Tissue Engineering
Abstract
Nowadays, post-surgical or post-accidental bone loss can be substituted by custom-made scaffolds fabricated by additive manufacturing (AM) methods from metallic powders. However, the partially melted powder particles must be removed in a post-process chemical treatment. The aim of this study was to investigate the effect of the chemical polishing with various acid baths on novel scaffolds' morphology, porosity and mechanical properties. In the first stage, Magics software (Materialise NV, Leuven, Belgium) was used to design a porous scaffolds with pore size equal to (A) 200 mu m, (B) 500 mu m and (C) 200 + 500 mu m, and diamond cell structure. The scaffolds were fabricated from commercially pure titanium powder (CP Ti) using a SLM50 3D printing machine (Realizer GmbH, Borchen, Germany). The selective laser melting (SLM) process was optimized and the laser beam energy density in range of 91-151 J/mm(3) was applied to receive 3D structures with fully dense struts. To remove not fully melted titanium particles the scaffolds were chemically polished using various HF and HF-HNO3 acid solutions. Based on scaffolds mass loss and scanning electron (SEM) observations, baths which provided most uniform surface cleaning were proposed for each porosity. The pore and strut size after chemical treatments was calculated based on the micro-computed tomography (mu-CT) and SEM images. The mechanical tests showed that the treated scaffolds had Young's modulus close to that of compact bone. Additionally, the effect of pore size of chemically polished scaffolds on cell retention, proliferation and differentiation was studied using human mesenchymal stem cells. Small pores yielded higher cell retention within the scaffolds, which then affected their growth. This shows that in vitro cell performance can be controlled to certain extent by varying pore sizes.