| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Świątkowski, Marcin
Lodz University of Technology
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (4/4 displayed)
- 2024Role of Climatic Cycles on the Duality of Chemical and Physical Modes of Sulfate Attack in Concrete
- 2022Design, Synthesis, and Characterization of Novel Coordination Compounds of Benzimidazole Derivatives with Cadmiumcitations
- 2022In Silico ADME and Toxicity Prediction of Benzimidazole Derivatives and Its Cobalt Coordination Compounds. Synthesis, Characterization and Crystal Structurecitations
- 2021Characterization of Metal-Bound Benzimidazole Derivatives, Effects on Tumor Cells of Lung Cancercitations
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article
Characterization of Metal-Bound Benzimidazole Derivatives, Effects on Tumor Cells of Lung Cancer
Abstract
Four new ligands and four new copper (II) coordination compounds were prepared andcharacterized by chemical, elemental analysis, cytotoxicity, and FTIR spectroscopy (Fourier transforminfrared spectroscopy). The nature of metal–ligand coordination was investigated. The thermalproperties of complexes in the solid state were studied using TG-MS techniques (thermogravimetricanalysis coupled with mass spectrometry) under dynamic flowing air atmosphere to analyze the principal volatile thermal decomposition and fragmentation products that evolved during thermolysis.The intermediate and final solid thermolysis products were also determined. The MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide) assay was used to evaluate active metaboliccells as an IC50 (half maximal inhibitory concentration). The relationship between antitumor activityand the position of nitrogen atoms in the organic ligand has been shown.