| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Teske, Michael
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (18/18 displayed)
- 2022Characterization of Ball-milled Poly(Nisopropylacrylamide) Nanogels
- 2022The influence of PEGDA’s molecular weight on its mechanical properties in the context of biomedical applicationscitations
- 2021A hydrogel based quasi-stationary test system for in vitro dexamethasone release studies for middle ear drug delivery systems
- 2020Smart releasing electrospun nanofibers-poly: L.lactide fibers as dual drug delivery system for biomedical application.citations
- 2020PEGDA drug delivery scaffolds manufactured with a novel hybrid AM process
- 20193D-printed PEGDA structure with multiple depots for advanced drug delivery systems
- 2019A Novel Hybrid Additive Manufacturing Process for Drug Delivery Systems with Locally Incorporated Drug Depots. citations
- 2019Thermomechanical properties of PEGDA in combination with different photo-curable comonomerscitations
- 2019Controlled biodegradation of metallic biomaterials by plasma polymer coatings using hexamethyldisiloxane and allylamine monomerscitations
- 2018Thermomechanical properties of PEGDA and its co-polymerscitations
- 2018Novel approach for a PTX/VEGF dual drug delivery system in cardiovascular applications-an innovative bulk and surface drug immobilization.citations
- 2017Osteointegration of Porous Poly-ε-Caprolactone-Coated and Previtalised Magnesium Implants in Critically Sized Calvarial Bone Defects in the Mouse Model. citations
- 2017In Vitro Evaluation of PCL and P(3HB) as Coating Materials for Selective Laser Melted Porous Titanium Implants. citations
- 2017Influence of bulk incorporation of FDAc and PTX on polymer propertiescitations
- 2015Comparison of Selective Laser Melted Titanium and Magnesium Implants Coated with PCL
- 2015Surface Modification of Biodegradable Polymers towards Better Biocompatibility and Lower Thrombogenicity.citations
- 2015Comparison of Selective Laser Melted Titanium and Magnesium Implants Coated with PCL.citations
- 2015SLM produced porous titanium implant improvements for enhanced vascularization and osteoblast seeding.citations
Places of action
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article
Osteointegration of Porous Poly-ε-Caprolactone-Coated and Previtalised Magnesium Implants in Critically Sized Calvarial Bone Defects in the Mouse Model.
Abstract
Metallic biomaterials are widely used in maxillofacial surgery. While titanium is presumed to be the gold standard, magnesium-based implants are a current topic of interest and investigation due to their biocompatible, osteoconductive and degradable properties. This study investigates the effects of poly-ε-caprolactone-coated and previtalised magnesium implants on osteointegration within murine calvarial bone defects: After setting a 3 mm × 3 mm defect into the calvaria of 40 BALB/c mice the animals were treated with poly-ε-caprolactone-coated porous magnesium implants (without previtalisation or previtalised with either osteoblasts or adipose derived mesenchymal stem cells), porous Ti6Al4V implants or without any implant. To evaluate bone formation and implant degradation, micro-computertomographic scans were performed at day 0, 28, 56 and 84 after surgery. Additionally, histological thin sections were prepared and evaluated histomorphometrically. The outcomes revealed no significant differences within the differently treated groups regarding bone formation and the amount of osteoid. While the implant degradation resulted in implant shifting, both implant geometry and previtalisation appeared to have positive effects on vascularisation. Although adjustments in degradation behaviour and implant fixation are indicated, this study still considers magnesium as a promising alternative to titanium-based implants in maxillofacial surgery in future.