| People | Locations | Statistics |
|---|---|---|
| Naji, M. |
| |
| Motta, Antonella |
| |
| Aletan, Dirar |
| |
| Mohamed, Tarek |
| |
| Ertürk, Emre |
| |
| Taccardi, Nicola |
| |
| Kononenko, Denys |
| |
| Petrov, R. H. | Madrid |
|
| Alshaaer, Mazen | Brussels |
|
| Bih, L. |
| |
| Casati, R. |
| |
| Muller, Hermance |
| |
| Kočí, Jan | Prague |
|
| Šuljagić, Marija |
| |
| Kalteremidou, Kalliopi-Artemi | Brussels |
|
| Azam, Siraj |
| |
| Ospanova, Alyiya |
| |
| Blanpain, Bart |
| |
| Ali, M. A. |
| |
| Popa, V. |
| |
| Rančić, M. |
| |
| Ollier, Nadège |
| |
| Azevedo, Nuno Monteiro |
| |
| Landes, Michael |
| |
| Rignanese, Gian-Marco |
|
Lodeiro, Carlos
Universidade Nova de Lisboa
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (25/25 displayed)
- 2023Diphenyl ditelluride assisted synthesis of noble metal-based silver-telluride 2D organometallic nanofibers with enhanced aggregation-induced emission (AIE) after oleylamine treatment
- 2020Thermochromic and acidochromic properties of polymer films doped with pyridyl-β-diketonate boron(III) complexescitations
- 2020Aggregation-induced emission enhancement (AIEE)-active Pt(II) metallomesogens as dyes sensitive to Hg2+ and dopant agents to develop stimuli-responsive luminescent polymer materialscitations
- 2019Highly accessible aqueous synthesis of well-dispersed dendrimer type platinum nanoparticles and their catalytic applicationscitations
- 2019Exploring the control in antibacterial activity of silver triangular nanoplates by surface coating modulationcitations
- 2017Synthesis and Characterization of PtTe2 Multi-Crystallite Nanoparticles using Organotellurium Nanocompositescitations
- 2017Supercritical CO2-assisted spray drying of strawberry-like gold-coated magnetite nanocomposites in chitosan powders for inhalationcitations
- 2017Synthesis and characterization of PtTeâ‚‚ multi-crystallite nanoparticles using organotellurium nanocomposites
- 2017A seleno-pyrene selective probe for Hg2+ detection in either aqueous or aprotic systemscitations
- 2016The interaction of Hg2+ and trivalent ions with two new fluorescein bio-inspired dual colorimetric/fluorimetric probescitations
- 2016Study of multiporphyrin compounds as colorimetric sitting-atop metal complexescitations
- 2016Novel trans-disubstituted hexaaza-macrocyclic ligands containing pyridine head units: Synthesis, disubstitution and colorimetric propertiescitations
- 2015Novel nanocomposites based on a strawberry-like gold- coated magnetite (Fe@Au) for protein separation in multiple myeloma serum samplescitations
- 2014Columnar discotic Pt(II) metallomesogens as luminescence multifunctional materials with chemo and thermosensor abilitiescitations
- 2014A new 3,5-bisporphyrinylpyridine derivative as a fluorescent ratiometric probe for zinc ionscitations
- 2014Bioinspired Functionalized Nanoparticles as Tools for Detection, Quantification and Targeting of Biomolecules
- 2013Zn 2+ /Cd 2+ optical discrimination by fluorescent chemosensors based on 8-hydroxyquinoline derivatives and sulfur-containing macrocyclic unitscitations
- 2013Zn2+/Cd2+ optical discrimination by fluorescent chemosensors based on 8-hydroxyquinoline derivatives and sulfur-containing macrocyclic unitscitations
- 2012New quinoline α-diimine ligands as fluorescent probes for metal ions: Ultrasound-assisted and conventional synthetic methodscitations
- 2012Novel emissive phenylurea-based macrocyclic chemosensor: Synthesis, fluorescent and complexation studiescitations
- 2012Novel emissive podands based on 8-OH-quinoline: Synthesis, fluorescence materials, DFT and complexation studiescitations
- 2011Novel small stable gold nanoparticles bearing fluorescent cysteine-coumarin probes as new metal-modulated chemosensorscitations
- 2011Bio-inspired systems for metal ion sensing : new emissive peptide probes based on benzo[d]oxazole derivatives and their gold and silica nanoparticlescitations
- 2010Hg2+ detection by new anthracene pendant-arm derivatives of mixed N/S- and N/S/O-donor macrocycles: Fluorescence, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and density functional theory studiescitations
- 2003Complexation of aluminum(III) by anthocyanins and synthetic flavylium salts: a source for blue and purple colorcitations
Places of action
| Organizations | Location | People |
|---|
article
Supercritical CO2-assisted spray drying of strawberry-like gold-coated magnetite nanocomposites in chitosan powders for inhalation
Abstract
Lung cancer is one of the leading causes of death worldwide. Therefore, it is of extreme importance to develop new systems that can deliver anticancer drugs into the site of action when initiating a treatment. Recently, the use of nanotechnology and particle engineering has enabled the development of new drug delivery platforms for pulmonary delivery. In this work, POXylated strawberry-like gold-coated magnetite nanocomposites and ibuprofen (IBP) were encapsulated into a chitosan matrix using Supercritical Assisted Spray Drying (SASD). The dry powder formulations showed adequate morphology and aerodynamic performances (fine particle fraction 48%-55% and aerodynamic diameter of 2.6-2.8 μm) for deep lung deposition through the pulmonary route. Moreover, the release kinetics of IBP was also investigated showing a faster release of the drug at pH 6.8, the pH of lung cancer. POXylated strawberry-like gold-coated magnetite nanocomposites proved to have suitable sizes for cellular internalization and their fluorescent capabilities enable their future use in in vitro cell based assays. As a proof-of-concept, the reported results show that these nano-in-micro formulations could be potential drug vehicles for pulmonary administration. © 2017 by the authors.