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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Liverani, Liliana
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (30/30 displayed)
- 2024Cotton wool-like ion-doped bioactive glass nanofibers: investigation of Zn and Cu combined effectcitations
- 2023Progress on Electrospun Composite Fibers Incorporating Bioactive Glass: An Overviewcitations
- 2023IVM Advances for Early Antral Follicle-Enclosed Oocytes Coupling Reproductive Tissue Engineering to Inductive Influences of Human Chorionic Gonadotropin and Ovarian Surface Epithelium Coculturecitations
- 2023Cotton-wool-like borosilicate glass fibers for tissue regeneration: Preparation, characterization and in vitro bioactivitycitations
- 2022When Electrospun Fiber Support Matters: In Vitro Ovine Long-Term Folliculogenesis on Poly (Epsilon Caprolactone) (PCL)-Patterned Fiberscitations
- 2022Poly(Glycerol Succinate) as Coating Material for 1393 Bioactive Glass Porous Scaffolds for Tissue Engineering Applicationscitations
- 2022Scaffold-Mediated Immunoengineering as Innovative Strategy for Tendon Regenerationcitations
- 2022Environmentally friendly fabrication of electrospun nanofibers made of polycaprolactone, chitosan and κ-carrageenan (PCL/CS/κ-C)citations
- 2021Polymer-Derived Biosilicate®-like Glass-Ceramics: Engineering of Formulations and Additive Manufacturing of Three-Dimensional Scaffoldscitations
- 2021Sol–Gel Synthesis and Characterization of YSZ Nanofillers for Dental Cements at Different Temperaturescitations
- 2021Synthesis and Characterization of Mesoporous Mg- and Sr-Doped Nanoparticles for Moxifloxacin Drug Delivery in Promising Tissue Engineering Applicationscitations
- 2021Preparation and characterization of sintered bioactive borate glass tapecitations
- 2021Production of a novel poly(ɛ‐caprolactone)‐methylcellulose electrospun wound dressing by incorporating bioactive glass and Manuka honeycitations
- 2021Polymer (PCL) fibers with Zn‐doped mesoporous bioactive glass nanoparticles for tissue regenerationcitations
- 2020Electrospun PCL Fiber Mats Incorporating Multi-Targeted B and Co Co-Doped Bioactive Glass Nanoparticles for Angiogenesiscitations
- 2020Polycaprolactone Electrospun Fiber Mats Prepared Using Benign Solvents: Blending with Copper(II)‐Chitosan Increases the Secretion of Vascular Endothelial Growth Factor in a Bone Marrow Stromal Cell Linecitations
- 2020Electrospun PCL/PGS Composite Fibers Incorporating Bioactive Glass Particles for Soft Tissue Engineering Applicationscitations
- 2020Poly(hydroxyalkanoate)s meet benign solvents for electrospinningcitations
- 2020Manuka honey and bioactive glass impart methylcellulose foams with antibacterial effects for wound-healing applicationscitations
- 2020Incorporation of Bioactive Glasses Containing Mg, Sr, and Zn in Electrospun PCL Fibers by Using Benign Solventscitations
- 2020A New Generation of Electrospun Fibers Containing Bioactive Glass Particles for Wound Healingcitations
- 2019Electrospun Filaments Embedding Bioactive Glass Particles with Ion Release and Enhanced Mineralizationcitations
- 2019Polyglycerol Hyperbranched Polyesters: Synthesis, Properties and Pharmaceutical and Biomedical Applicationscitations
- 2019Electrospun patterned porous scaffolds for the support of ovarian follicles growth: a feasibility studycitations
- 2019Effect of benign solvents composition on poly(ε-caprolactone) electrospun fiber propertiescitations
- 2019Bioactive behavior of mesoporous silica particle (MCM‐41) coated bioactive glass‐based scaffoldscitations
- 2019Novel biomimetic fiber incorporated scaffolds for tissue engineeringcitations
- 2018Numerical simulation of electrospinning process in commercial and in-house software PAKcitations
- 2016Versatile Production of Poly(Epsilon-Caprolactone) Fibers by Electrospinning Using Benign Solventscitations
- 2016Synthesis of Monodispersed Ag-Doped Bioactive Glass Nanoparticles via Surface Modificationcitations
Places of action
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article
Synthesis and Characterization of Mesoporous Mg- and Sr-Doped Nanoparticles for Moxifloxacin Drug Delivery in Promising Tissue Engineering Applications
Abstract
<p>Mesoporous silica-based nanoparticles (MSNs) are considered promising drug carriers because of their ordered pore structure, which permits high drug loading and release capacity. The dissolution of Si and Ca from MSNs can trigger osteogenic differentiation of stem cells towards extracellular matrix calcification, while Mg and Sr constitute key elements of bone biology and metabolism. The aim of this study was the synthesis and characterization of sol–gel-derived MSNs codoped with Ca, Mg and Sr. Their physico-chemical properties were investigated by X-ray diffraction (XRD), scanning electron microscopy with energy dispersive X-ray analysis (SEM/EDX), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), X-ray fluorescence spectroscopy (XRF), Brunauer Emmett Teller and Brunauer Joyner Halenda (BET/BJH), dynamic light scattering (DLS) and ζ-potential measurements. Moxifloxacin loading and release profiles were assessed with high performance liquid chromatography (HPLC) cell viability on human periodontal ligament fibroblasts and their hemolytic activity in contact with human red blood cells (RBCs) at various concentrations were also investigated. Doped MSNs generally retained their textural characteristics, while different compositions affected particle size, hemolytic activity and moxifloxacin loading/release profiles. All co-doped MSNs revealed the formation of hydroxycarbonate apatite on their surface after immersion in simulated body fluid (SBF) and promoted mitochondrial activity and cell proliferation.</p>