| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Arif, Muhammad
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (8/8 displayed)
- 2024DPI_CDF: druggable protein identifier using cascade deep forestcitations
- 2024Unified mRNA Subcellular Localization Predictor based on machine learning techniquescitations
- 2023Photocatalytic Reduction of Cr(VI) to Cr(III) and Photocatalytic Degradation of Methylene Blue and Antifungal Activity of Ag/TiO2 Composites Synthesized via the Template Induced Routecitations
- 2023Association of GSTTI, M1 and Polymorphism in GSTPI with Chronic Periodontal Disease in a Pakistani Populationcitations
- 2022Process parameter optimization for Fused Filament Fabrication additive manufacturing of PLA/PHA biodegradable polymer blendcitations
- 2018Effect of surfactant concentration in electrolyte on the fabrication and properties of nickel-graphene nanocomposite coating synthesized by electrochemical co-depositioncitations
- 2018Increased interference fringe visibility from the post-fabrication heat treatment of a perfect crystal silicon neutron interferometer
- 2017Increased interference fringe visibility from the post fabrication heat treatment of a perfect crystal silicon neutron interferometercitations
Places of action
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article
Association of GSTTI, M1 and Polymorphism in GSTPI with Chronic Periodontal Disease in a Pakistani Population
Abstract
<jats:p>Objective: Chronic periodontal disease (CP) is a multifactorial infectious and inflammatory disease that occurs due to the challenge between the immune response of the host and specific periodontal bacteria, and that can lead to tooth loss due to damage inflicted to the supporting tissue. The current study investigates the genotypes of the GSTM1 and GSTT1 genes, along with the allelic frequency of the single nucleotide polymorphism [SNP; rs1695] in the GSTP1 gene and correlates them individually or in various combinations with the incidence of CP. Methods: A total of 203 clinically confirmed CP patients and 201 control subjects were enrolled from Multan and Dera Ghazi Khan Districts in Pakistan from April to July 2022. Multiplex Polymerase Chain Reaction (PCR) and tetra-primer amplification refractory mutation system–polymerase chain reaction (T-ARMS–PCR) approaches were applied to determine the genotypes of the studied GSTs. The association of rs1695 in GSTP1 with CP was studied both individually and in various combinations with GSTM1 and T1. Results: The absence of GSTM1, the presence of GSTT1 and the presence of the mutant allele (G) at rs1695 in GSTP1 were found to be significantly associated with CP. Patients aged between 10 and 30 years were more affected by CP. Conclusion: Our results indicate that the genotypes of the analyzed GSTs affect the levels of protection from oxidative stress and may therefore influence the disease progression in CP.</jats:p>