| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Tovar, Nick
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (14/14 displayed)
- 20233D Printing Type 1 Bovine Collagen Scaffolds for Tissue Engineering Applications—Physicochemical Characterization and In Vitro Evaluationcitations
- 2023Engineering 3D Printed Bioceramic Scaffolds to Reconstruct Critical-Sized Calvaria Defects in a Skeletally Immature Pig Modelcitations
- 2022Residual stress estimated by nanoindentation in pontics and abutments of veneered zirconia fixed dental prosthesescitations
- 2022Physiochemical and bactericidal activity evaluationcitations
- 2021Three-Dimensionally-Printed Bioactive Ceramic Scaffoldscitations
- 2021Effect of supplemental acid-etching on the early stages of osseointegrationcitations
- 2020Assessing osseointegration of metallic implants with boronized surface treatmentcitations
- 2019Synergistic effects of implant macrogeometry and surface physicochemical modifications on osseointegrationcitations
- 2019Repair of Critical-Sized Long Bone Defects Using Dipyridamole-Augmented 3D-Printed Bioactive Ceramic Scaffoldscitations
- 2018Form and functional repair of long bone using 3D-printed bioactive scaffoldscitations
- 2014The physicochemical characterization and in vivo response of micro/nanoporous bioactive ceramic particulate bone graft materialscitations
- 2014The in vivo effect of P-15 coating on early osseointegrationcitations
- 2014Nanometer-scale features on micrometer-scale surface texturingcitations
- 2012Physicochemical characterization and in vivo evaluation of amorphous and partially crystalline calcium phosphate coatings fabricated on Ti-6Al-4V implants by the plasma spray methodcitations
Places of action
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article
3D Printing Type 1 Bovine Collagen Scaffolds for Tissue Engineering Applications—Physicochemical Characterization and In Vitro Evaluation
Abstract
<jats:p>Collagen, an abundant extracellular matrix protein, has shown hemostatic, chemotactic, and cell adhesive characteristics, making it an attractive choice for the fabrication of tissue engineering scaffolds. The aim of this study was to synthesize a fibrillar colloidal gel from Type 1 bovine collagen, as well as three dimensionally (3D) print scaffolds with engineered pore architectures. 3D-printed scaffolds were also subjected to post-processing through chemical crosslinking (in N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide) and lyophilization. The scaffolds were physicochemically characterized through Fourier Transform Infrared Spectroscopy (FTIR), Thermogravimetric Analysis, Differential Scanning Calorimetry, and mechanical (tensile) testing. In vitro experiments using Presto Blue and Alkaline Phosphatase assays were conducted to assess cellular viability and the scaffolds’ ability to promote cellular proliferation and differentiation. Rheological analysis indicated shear thinning capabilities in the collagen gels. Crosslinked and lyophilized 3D-printed scaffolds were thermally stable at 37 °C and did not show signs of denaturation, although crosslinking resulted in poor mechanical strength. PB and ALP assays showed no signs of cytotoxicity as a result of crosslinking. Fibrillar collagen was successfully formulated into a colloidal gel for extrusion through a direct inkjet writing printer. 3D-printed scaffolds promoted cellular attachment and proliferation, making them a promising material for customized, patient-specific tissue regenerative applications.</jats:p>