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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Kanoun, Olfa
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (19/19 displayed)
- 2024Enhancement of the Potential Window of Ppy Electrodes in the Presence of a Bis(Oxamato) Nickel(II) Complex for High‐Performance Supercapacitor
- 2023Synergy of nanocomposite force myography and optical fiber-based wrist angle sensing for ambiguous sign classification
- 2023Novel Sensitive Electrochemical Immunosensor Development for the Selective Detection of HopQ H. pylori Bacteria Biomarkercitations
- 2022Role of Solvent Polarity on Dispersion Quality and Stability of Functionalized Carbon Nanotubescitations
- 2022Gold Nanoparticles-MWCNT Based Aptasensor for Early Diagnosis of Prostate Cancercitations
- 2021A review of nanocomposite-modified electrochemical sensors for water quality monitoringcitations
- 2021Flexible Ultra-Thin Nanocomposite Based Piezoresistive Pressure Sensors for Foot Pressure Distribution Measurementcitations
- 2021A Review of Nanocomposite-Modified Electrochemical Sensors for Water Quality Monitoringcitations
- 2019Highly sensitive capacitive pressure sensors for robotic applications based on carbon nanotubes and PDMS polymer nanocompositecitations
- 2019Experimental Setup for Examination of the Roll Gap during a Rolling Process
- 2019Non-contacting Velocity Measurement of hot Rod and Wire using Eddy-current Sensors
- 2019Velocity Approximation of Hot Steel Rods Using Frequency Spectroscopy of the Cross-Section Area
- 2019Temperature Self-Compensated Strain Sensors based on MWCNT-Graphene Hybrid Nanocompositecitations
- 2019Ion-Imprinted Electrochemical Sensor Based on Copper Nanoparticles-Polyaniline Matrix for Nitrate Detectioncitations
- 2019Humidity Sensing Behavior of Endohedral Li-Doped and Undoped SWCNT/SDBS Composite Filmscitations
- 2018Roll Gap Measurement in Rolling Mills Using Impedance Analysis – A First Experimental Setup with a Pot Core Coil as Sensor
- 2017Controlling the crack formation in inkjet-printed silver nanoparticle thin-films for high resolution patterning using intense pulsed light treatmentcitations
- 2016Electromechanical Behavior of Chemically Reduced Graphene Oxide and Multi-walled Carbon Nanotube Hybrid Materialcitations
- 2015Temperature-Compensated Force/Pressure Sensor Based on Multi-Walled Carbon Nanotube Epoxy Compositescitations
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article
Gold Nanoparticles-MWCNT Based Aptasensor for Early Diagnosis of Prostate Cancer
Abstract
<jats:p>Prostate cancer is one of the most frequently diagnosed male malignancies and can be detected by prostate-specific antigen (PSA) as a biomarker. To detect PSA, several studies have proposed using antibodies, which are not economical and require a long reaction time. In this study, we propose to use self-assembled thiolated single-strand DNA on electrodes functionalized by multi-walled carbon nanotubes (MWCNT) modified with gold nanoparticles (AuNPs) to realize a low-cost label-free electrochemical biosensor. In this regard, the PSA aptamer was immobilized via electrostatic adsorption on the surface of a screen-printed MWCNT/AuNPs electrode. The immobilization process was enhanced due to the presence of Au nanoparticles on the surface of the electrode. Surface characterization of the electrode at different stages of modification was performed by electrochemical impedance spectroscopy (EIS), atomic force microscopy (AFM) and Fourier transform infrared spectroscopy (FTIR) and contact angle for surface tension properties. The results showed an increase in surface roughness due to the absorbance of the aptamer on the electrode surfaces. The developed sensor has an extended linear range of 1–100 ng/mL, and a very low limit of detection down to 1 pg/mL. In addition, the reaction has a binding time of only five minutes on the developed electrodes. Investigations of the biosensor selectivity against several substances revealed an efficient selectivity for PSA detection. With this approach, low-cost biosensors with high sensitivity can be realized which have a wide linearity range and a low limit of detection, which are necessary for the early detection of prostate cancer.</jats:p>