| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Dandurand, Jany
Université Toulouse III - Paul Sabatier
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (27/27 displayed)
- 2022Continuous Bamboo Fibers/Fire-Retardant Polyamide 11: Dynamic Mechanical Behavior of the Biobased Compositecitations
- 2020Thermogravimetric study of the behaviour of organic and inorganic polymers contained in four dental resin-based compositescitations
- 2020Biophysical and lipidomic biomarkers of cardiac remodeling post-myocardial infarction in humanscitations
- 2019Thermal, mechanical and dielectric behaviour of poly(aryl ether ketone) with low melting temperaturecitations
- 2019Mechanical properties of continuous bamboo fiber-reinforced biobased polyamide 11 compositescitations
- 2018Dynamic relaxations in a bio-based polyamide with enhanced mechanical moduluscitations
- 2017Physical structure and mechanical properties of polyamide/bamboo compositescitations
- 2017Identification of ageing biomarkers in human dermis biopsies by thermal analysis (DSC) combined with Fourier transform infrared spectroscopy (FTIR/ATR).citations
- 2016Mechanical and thermal behaviour of bamboo flour-reinforced XLPE compositescitations
- 2015Polymerization study and rheological behavior of a RTM6 epoxy resin system during preprocessing stepcitations
- 2015New hybrid polymer nanocomposites for passive vibration damping by incorporation of carbon nanotubes and lead zirconate titanate particlescitations
- 2014Conformational and thermal characterization of a synthetic peptidic fragment inspired from human tropoelastin: Signature of the amyloid fiberscitations
- 2014Discontinuity of physical properties of carbon nanotube/polymer composites at the percolation thresholdcitations
- 2014Electrical and Piezoelectric Behavior of Polyamide/PZT/CNT Multifunctional Nanocompositescitations
- 2014Integrated piezoelectric function in a high thermostable thermoplastic PZT/PEEK compositecitations
- 2013Dielectric relaxations in PEEK by combined dynamic dielectric spectroscopy and thermally stimulated currentcitations
- 2011Dynamic mechanical properties of oral mucosa: comparison with polymeric soft denture liners.citations
- 2011Molecular mobility in piezoelectric hybrid nanocomposites with 0-3 connectivity: Particles size influencecitations
- 2011Molecular mobility in piezoelectric hybrid nanocomposites with 0–3 connectivity: Volume fraction influencecitations
- 2011Influence of hydrogen bonds on glass transition and dielectric relaxations of cellulosecitations
- 2010Dynamic mechanical behaviour of polyamide 11/Barium titanate ferroelectric compositescitations
- 2008Thermally stimulated current and dielectric relaxation of inorganic/organic ferroelectric nanocomposites
- 2007Dynamic Mechanical Properties of a Biomimetic Hydroxyapatite/Polyamide 6,9 Nanocompositecitations
- 2007Electroactive influence of ferroelectric nanofillers on polyamide 11 matrix propertiescitations
- 2006Thermo-mechanical analysis of dental silicone polymerscitations
- 2004TSC and Broadband Dielectric Spectroscopy Studies of the α Relaxation in Phosphorus-Containing Dendrimerscitations
- 2002Enthalpy Relaxation in Phosphorus-Containing Dendrimerscitations
Places of action
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article
Biophysical and lipidomic biomarkers of cardiac remodeling post-myocardial infarction in humans
Abstract
Few studies have analyzed the potential of biophysical parameters as markers of cardiac remodeling post-myocardial infarction (MI), particularly in human hearts. Fourier transform infrared spectroscopy (FTIR) illustrates the overall changes in proteins, nucleic acids and lipids in a single signature. The aim of this work was to define the FTIR and lipidomic pattern for human left ventricular remodeling post-MI. A total of nine explanted hearts from ischemic cardiomyopathy patients were collected. Samples from the right ventricle (RV), left ventricle (LV) and infarcted left ventricle (LV INF) were subjected to biophysical (FTIR and differential scanning calorimetry, DSC) and lipidomic (liquid chromatography–high-resolution mass spectrometry, LC–HRMS) studies. FTIR evidenced deep alterations in the myofibers, extracellular matrix proteins, and the hydric response of the LV INF compared to the RV or LV from the same subject. The lipid and esterified lipid FTIR bands were enhanced in LV INF, and both lipid indicators were tightly and positively correlated with remodeling markers such as collagen, lactate, polysaccharides, and glycogen in these samples. Lipidomic analysis revealed an increase in several species of sphingomyelin (SM), hexosylceramide (HexCer), and cholesteryl esters combined with a decrease in glycerophospholipids in the infarcted tissue. Our results validate FTIR indicators and several species of lipids as useful markers of left ventricular remodeling post-MI in humans.