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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Pessanha, Sofia
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2023Maternal methylmercury exposure during early-life periods adversely affects mature enamel structure of offspring rats at human exposure levelscitations
- 2022Characterization of binders and pigments using an integrated analytical approach: Application to wooden reliefs created by Vasko Lipovac in the 1970scitations
- 2021Investigation of inks, pigments and paper in four Moroccan illuminated manuscripts dated to the eighteenth centurycitations
- 2020Evaluation of the effect of fluorinated tooth bleaching products using polarized Raman microscopy and particle induced gamma-ray emissioncitations
- 2019Josefa d' Óbidos workshop from panel to canvas. Multianalytical approach to materials and technical evolution of the most significant Portuguese painting workshop of the 17 th centurycitations
- 2016Distribution of toxic elements in teeth treated with amalgam using mu-energy dispersive X-ray fluorescencecitations
- 2016Jose de Escovar at the Chapel of the Souls: Technical and material study of a 1603 panel painting
- 2016Artificial aging paper to assess long-term effects of conservative treatment. Monitoring by infrared spectroscopy (ATR-FTIR), X-ray diffraction (XRD), and energy dispersive X-ray fluorescence (EDXRF)citations
- 2015Microscopy and X-Ray Spectroscopy Analyses for assessment gilding and silvering techniques of Portuguese illuminated manuscriptscitations
- 2015Nondestructive analysis of Portuguese “dinheiros” using XRF: overcoming patina constraintscitations
- 2009Comparison of matrix effects on portable and stationary XRF spectrometers for cultural heritage samplescitations
- 2009Efficacy of Waterborne Polyurethane to Prevent the Enzymatic Attack on Paper-Based Materialscitations
- 2008Analysis of a coloured Dutch map from the eighteenth centurycitations
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article
Maternal methylmercury exposure during early-life periods adversely affects mature enamel structure of offspring rats at human exposure levels
Abstract
Although there are many studies on the health effects of methylmercury (MeHg) toxicity during in utero and early development, little is known about its effects on mineralized tissues present in the oral cavity, such as enamel structure. Therefore, this study evaluated the effects of MeHg exposure on the physico-chemical, ultrastructural and functional properties of mature tooth enamel. Specifically, we studied offspring of mothers exposed to MeHg during the prenatal and postnatal periods which are the developmental stages associated with tooth enamel formation. Female rats were exposed to MeHg at a dose of 40 μg/kg/day for 42 days of pregnancy and lactation. The enamel of offspring was analyzed by (1) Fourier Transform Infrared Spectroscopy and Raman to assess physicochemical composition, (2) Scanning Electron Microscopy for ultrastructural evaluation, (3) Transmitted Polarizing Light Microscopy for analysis of the enamel extracellular matrix, and (4) resistance and hardness were evaluated by microhardness. The results showed that MeHg exposure during this sensitive enamel formation period induced changes in inorganic and organic content and enamel prisms ultrastructure alterations and disturbed the organic extracellular matrix due to a decreased enamel strength. These novel findings establish for the first time that maternal exposure to MeHg pre and postnatal promoted relevant changes in mature enamel of their offspring rats.