| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Navarro, M.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (28/28 displayed)
- 2022Evaluation of Fourier Transform Infrared Spectroscopy as a First-Line Typing Tool for the Identification of Extended-Spectrum β-Lactamase-Producing <i>Klebsiella pneumoniae</i> Outbreaks in the Hospital Setting.citations
- 2019Influence of the addition of fibers in different phases of the spinning process on the behaviour of cotton blended yarns
- 2019Influence of the addition of nettle and hemp fibers to cotton based yarns on the moisture management properties
- 2014Role of porosity and pore architecture in the in vivo bone regeneration capacity of biodegradable glass scaffoldscitations
- 2011Electrochemical treatment to condition contaminated EAFD as addition to immobilisation mortar in low level waste concrete containerscitations
- 2010Materials surface effects on biological interactionscitations
- 2008A novel hybrid calcium phosphate/ACP injectable cement
- 2008Of the in vivo behavior of calcium phosphate cements and glasses as bone substitutescitations
- 2008Surface characterization and cell response of a PLA/CaP glass biodegradable composite materialcitations
- 2007Micro and nanostructure evolution study of novel injectable calcium phosphate cements prepared by ceramic and sol-gel processes
- 2006Development of a biodegradable composite scaffold for bone tissue engineeringcitations
- 2006Transparent micro- and nanopatterned poly(lactic acid) for biomedical applicationscitations
- 2005In vivo behavior of calcium phosphate glasses with controlled solubilitycitations
- 2005Surface characterization of completely degradable composite scaffoldscitations
- 2005In vitro degradation behavior of a novel bioresorbable composite material based on PLA and a soluble CaP glasscitations
- 2004Development and cell response of a new biodegradable composite scaffold for guided bone regenerationcitations
- 2004Macroporous calcium phosphate glass ceramic scaffold for bone regeneration
- 2004New macroporous calcium phosphate glass ceramic for guided bone regenerationcitations
- 2004Calcium phosphate bone substitutes.
- 2004Control de la velocidad de degradación de materiales compuestos para aplicacions biomédicas
- 2004Development of a new calcium phosphate glass ceramic porous scaffold for guided bone regenerationcitations
- 2004Control de la velocidad de degradación de materiales compuestos para aplicaciones biomédicas.
- 2003Cellular response to calcium phosphate glasses with controlled solubilitycitations
- 2003Physicochemical degradation of titania-stabilized soluble phosphate glasses for medical applicationscitations
- 2002Improvement of the stability and mechanical properties of resorbable phosphate glasses by the addition of TiO2citations
- 2002Improvement of the stability and mechanical properties of resorbable phosphate glasses by the addition of TIO<inf>2</inf>
- 2001Chemical durability and mechanical properties of calcium phosphate glasses with the addition of Fe<inf>2</inf>O<inf>3</inf>, TiO<inf>2</inf> and ZnO
- 2000Chemical durability and mechanical properties of calcium phosphate glasses with the addition of Fe2O3, TiO2 and ZnO
Places of action
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article
Evaluation of Fourier Transform Infrared Spectroscopy as a First-Line Typing Tool for the Identification of Extended-Spectrum β-Lactamase-Producing <i>Klebsiella pneumoniae</i> Outbreaks in the Hospital Setting.
Abstract
Early detection of pathogen cross-transmission events and environmental reservoirs is needed to control derived nosocomial outbreaks. Whole-genome sequencing (WGS) is considered the gold standard for outbreak confirmation, but, in most cases, it is time-consuming and has elevated costs. Consequently, the timely incorporation of WGS results to conventional epidemiology (CE) investigations for rapid outbreak detection is scarce. Fourier transform infrared spectroscopy (FTIR) is a rapid technique that establishes similarity among bacteria based on the comparison of infrared light absorption patterns of bacterial polysaccharides and has been used as a typing tool in recent studies. The aim of the present study was to evaluate the performance of the FTIR as a first-line typing tool for the identification of extended-spectrum β-lactamase-producing <i>Klebsiella pneumoniae</i> (ESBL-Kp) outbreaks in the hospital setting in comparison with CE investigations using WGS as the gold standard method. Sixty-three isolates of ESBL-Kp collected from 2018 to 2021 and classified according to CE were typed by both FTIR and WGS. Concordance was measured using the Adjusted Rand index (AR) and the Adjusted Wallace coefficient (AW) for both CE and FTIR clustering considering WGS as the reference method. Both AR and AW were significantly higher for FTIR clustering than CE clustering (0.475 vs. 0.134, <i>p</i> = 0.01, and 0.521 vs. 0.134, <i>p</i> = 0.009, respectively). Accordingly, FTIR inferred more true clustering relationships than CE (38/42 vs. 24/42, <i>p</i> = 0.001). However, a similar proportion of genomic singletons was detected by both FTIR and CE (13/21 vs. 12/21, <i>p</i> = 1). This study demonstrates the utility of the FTIR method as a quick, low-cost, first-line tool for the detection of ESBL-Kp outbreaks, while WGS analyses are being performed for outbreak confirmation and isolate characterization. Thus, clinical microbiology laboratories would benefit from integrating the FTIR method into CE investigations for infection control measures in the hospital setting.