| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Ali, Asif
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (8/8 displayed)
- 2024Mobile-UI-Repair: a deep learning based UI smell detection technique for mobile user interfacecitations
- 2024Zinc-doped phosphate coatings for enhanced corrosion resistance, antibacterial properties, and biocompatibility of AZ91D Mg alloycitations
- 2023Hydrothermal deposition of high strength biocompatible magnesium phosphate coating through in situ conversion of AZ91D-3Ca magnesium substratecitations
- 2021Improving the in vitro Degradation, Mechanical and Biological Properties of AZ91-3Ca Mg Alloy via Hydrothermal Calcium Phosphate Coatingscitations
- 2021Dielectric, ferroelectric and optical properties of Na and Nb co-doped (Bi0.5Na0.5)0.94Ba0.06TiO3 ; Діелектричні, сегнетоелектричні та оптичні властивості (Bi0,5Na0,5)0,94Ba0,06TiO3, легованого Na та Nb
- 2020Influence of calcined snail shell particulates on mechanical properties of recycled aluminium alloy for automotive applicationcitations
- 2019Hydrothermal deposition of high strength calcium phosphate coatings on magnesium alloy for biomedical applicationscitations
- 2019Mechanical Properties of Powder Metallurgy Processed Biodegradable Zn-Based Alloy for Biomedical Application
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article
Improving the in vitro Degradation, Mechanical and Biological Properties of AZ91-3Ca Mg Alloy via Hydrothermal Calcium Phosphate Coatings
Abstract
<jats:p>For many years, calcium phosphate coatings to tailor the degradation behavior of magnesium and magnesium-based alloys for orthopaedic applications have received lots of research attention. However, prolong degradation behavior, its effect on biological and mechanical properties as well as osteoblastic response to single-step hydrothermally deposited calcium phosphate coatings remain poorly documented. In this study, Alamar blue assay, cell attachment, live/dead assay, and qRT-PCR were done to study the biological response of the coatings. Furthermore, immersion testing in SBF for 28 days and compression testing of the degraded samples were carried out to examine the degradation behavior and its effect on mechanical properties. The results indicated that coatings have a significant influence on both the substrate performance and structural integrity of coated AZ91-3Ca alloy. Immersion test revealed that coating deposited at pH 7, 100°C (CP7100) improves the hydrogen evolution rate by 65% and the degradation rate by 60%. As the degradation performance of coated samples improves so does the mechanical strength. CP7100 samples successfully retained 90% of their compressive strength after 14 days of immersion while bare AZ91-3Ca alloy lost its mechanical integrity. Furthermore, biological studies show that cells are happily proliferating, differentiating, and adhering to the coating surfaces, which indicates, improved osteointegration and osteogenesis with no sign of alkaline poisoning. qRT-PCR results showed that calcium phosphate coatings enhanced the mRNA levels for <jats:italic>RUNX2</jats:italic>, <jats:italic>Col1A</jats:italic>, and <jats:italic>ALP</jats:italic> that may exhibit a speedy bone recovery. Thus, calcium phosphate coatings produced via a single-step hydrothermal method improve the degradation behavior, mechanical integrity and stimulate the differentiation of osteoblast lining. This leads toward faster bone regeneration, which shows a great potential of these coatings to be used on degradable implants as a bioactive protective layer.</jats:p>