| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Silva, Tiago H.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (47/47 displayed)
- 2025Corrigendum: Marine collagen-chitosan-fucoidan cryogels as cell-laden biocomposites envisaging tissue engineering (2020 Biomed. Mater. 15 055030)
- 2024<i>In</i><i> vivo</i> assessment of marine<i> vs</i> bovine origin collagen-based composite scaffolds promoting bone regeneration in a New Zealand rabbit modelcitations
- 2024The Characterization and Cytotoxic Evaluation of Chondrosia reniformis Collagen Isolated from Different Body Parts (Ectosome and Choanosome) Envisaging the Development of Biomaterialscitations
- 2024Extraction and Purification of Biopolymers from Marine Origin Sources Envisaging Their Use for Biotechnological Applicationscitations
- 2024From Its Nature to Its Function: Marine-Collagen-Based-Biomaterials for Hard Tissue Applicationscitations
- 2023Longitudinally aligned inner-patterned silk fibroin conduits for peripheral nerve regenerationcitations
- 2023Fucoidan-Coated Silica Nanoparticles Promote the Differentiation of Human Mesenchymal Stem Cells into the Osteogenic Lineagecitations
- 2023In Vivo Skin Hydrating Efficacy of Fish Collagen from Greenland Halibut as a High-Value Active Ingredient for Cosmetic Applicationscitations
- 2023Advanced Polymeric Membranes as Biomaterials Based on Marine Sources Envisaging the Regeneration of Human Tissuescitations
- 2023Marine Gelatin-Methacryloyl-Based Hydrogels as Cell Templates for Cartilage Tissue Engineeringcitations
- 2023Development of Cork Biocomposites Enriched with Chitosan Targeting Antibacterial and Antifouling Propertiescitations
- 2023Fucoidan from Fucus vesiculosus Inhibits Inflammatory Response, Both In Vitro and In Vivocitations
- 2023Structure and Composition of the Cuticle of the Goose Barnacle Pollicipes pollicipes: A Flexible Composite Biomaterialcitations
- 2023Building Fucoidan/Agarose-Based Hydrogels as a Platform for the Development of Therapeutic Approaches against Diabetescitations
- 2023Potential of Atlantic Codfish (Gadus morhua) Skin Collagen for Skincare Biomaterialscitations
- 2023Cell-Laden Marine Gelatin Methacryloyl Hydrogels Enriched with Ascorbic Acid for Corneal Stroma Regenerationcitations
- 2022Fucoidan-based hydrogels particles as versatile carriers for diabetes treatment strategiescitations
- 2022FUCOIDAN HYDROGELS SIGNIFICANTLY ALLEVIATE OXIDATIVE STRESS AND ENHANCE THE ENDOCRINE FUNCTION OF ENCAPSULATED BETA CELLS
- 2022Marine-Inspired Drugs and Biomaterials in the Perspective of Pancreatic Cancer Therapiescitations
- 2022Engineering of Viscosupplement Biomaterials for Treatment of Osteoarthritis: A Comprehensive Reviewcitations
- 2022Marine origin biomaterials using a compressive and absorption methodology as cell-laden hydrogel envisaging cartilage tissue engineeringcitations
- 2022Adhesive and biodegradable membranes made of sustainable catechol-functionalized marine collagen and chitosancitations
- 2022Glial Cell Line-Derived Neurotrophic Factor-Loaded CMCht/PAMAM Dendrimer Nanoparticles for Peripheral Nerve Repaircitations
- 2022Skin Byproducts of Reinhardtius hippoglossoides (Greenland Halibut) as Ecosustainable Source of Marine Collagencitations
- 2022Mineralized collagen as a bioactive ink to support encapsulation of human adipose stem cells: A step towards the future of bone regenerationcitations
- 2022Biomimetic Surface Topography from the <i>Rubus fruticosus</i> Leaf as a Guidance of Angiogenesis in Tissue Engineering Applicationscitations
- 2022A Design of Experiments (DoE) Approach to Optimize Cryogel Manufacturing for Tissue Engineering Applicationscitations
- 2021Marine-Derived Polymeric Nanostructures for Cancer Treatmentcitations
- 2021Bioactivity of Biosilica Obtained From North Atlantic Deep-Sea Spongescitations
- 2021<i>Prionace glauca</i> skin collagen bioengineered constructs as a promising approach to trigger cartilage regenerationcitations
- 2021Angiogenic potential of airbrushed fucoidan/polycaprolactone nanofibrous meshescitations
- 2021Innovative methodology for marine collagen-chitosan-fucoidan hydrogels production, tailoring rheological properties towards biomedical applicationcitations
- 2021Marine origin materials on biomaterials and advanced therapies to cartilage tissue engineering and regenerative medicinecitations
- 2021Diverse and Productive Source of Biopolymer Inspiration: Marine Collagenscitations
- 2021Macro and Microstructural Characteristics of North Atlantic Deep-Sea Sponges as Bioinspired Models for Tissue Engineering Scaffoldingcitations
- 2021Fucoidan Hydrogels Significantly Alleviate Oxidative Stress and Enhance the Endocrine Function of Encapsulated Beta Cellscitations
- 2021Engineering 3D printed bioactive composite scaffolds based on the combination of aliphatic polyester and calcium phosphates for bone tissue regenerationcitations
- 2021Fucoidan/chitosan nanoparticles functionalized with anti-ErbB-2 target breast cancer cells and impair tumor growth <i>in vivo</i>citations
- 2020Acid and enzymatic extraction of collagen from Atlantic cod (Gadus Morhua) swim bladders envisaging health-related applicationscitations
- 2020Extraction and Characterization of Collagen from Elasmobranch Byproducts for Potential Biomaterial Usecitations
- 2020Collagen from Atlantic cod (Gadus morhua) skins extracted using CO2 acidified water with potential application in healthcarecitations
- 2020Spatial immobilization of endogenous growth factors to control vascularization in bone tissue engineeringcitations
- 2014Surface modification of silica-based marine sponge bioceramics induce hydroxyapatite formationcitations
- 2014Bioactive ceramics for tissue engineering and regenerative medicine derived from marine sponges
- 2013Marine sponges : a new source of bioactive ceramics for tissue engineering and regenerative medicine applicationscitations
- 2013Unleashing the potential of supercritical fluids for polymer processing in tissue engineering and regenerative medicinecitations
- 2012Development of marine-based nanocomposite scaffolds for biomedical applications
Places of action
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article
Macro and Microstructural Characteristics of North Atlantic Deep-Sea Sponges as Bioinspired Models for Tissue Engineering Scaffolding
Abstract
<jats:p>Sponges occur ubiquitously in the marine realm and in some deep-sea areas they dominate the benthic communities forming complex biogenic habitats – sponge grounds, aggregations, gardens and reefs. However, deep-sea sponges and sponge-grounds are still poorly investigated with regards to biotechnological potential in support of a Blue growth strategy. Under the scope of this study, five dominant North Atlantic deep-sea sponges, were characterized to elucidate promising applications in human health, namely for bone tissue engineering approaches. <jats:italic>Geodia barretti</jats:italic> (Gb), <jats:italic>Geodia atlantica</jats:italic> (Ga), <jats:italic>Stelletta normani</jats:italic> (Sn), <jats:italic>Phakellia ventilabrum</jats:italic> (Pv), and <jats:italic>Axinella infundibuliformis</jats:italic> (Ai), were morphologically characterized to assess macro and microstructural features, as well as chemical composition of the skeletons, using optical and scanning electron microscopy, energy dispersive x-ray spectroscopy and microcomputed tomography analyses. Moreover, compress tests were conducted to determine the mechanical properties of the skeletons. Results showed that all studied sponges have porous skeletons with porosity higher than 68%, pore size superior than 149 μm and higher interconnectivity (&gt;96%), thus providing interesting models for the development of scaffolds for tissue engineering. Besides that, EDS analyses revealed that the chemical composition of sponges, pointed that demosponge skeletons are mainly constituted by carbon, silicon, sulfur, and oxygen combined mutually with organic and inorganic elements embedded its internal architecture that can be important features for promoting bone matrix quality and bone mineralization. Finally, the morphological, mechanical, and chemical characteristics here investigated unraveled the potential of deep-sea sponges as a source of biomaterials and biomimetic models envisaging tissue engineering applications for bone regeneration.</jats:p>