| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Persson, Cecilia
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (27/27 displayed)
- 2024Structural Si3N4-SiO2 glass ceramics with bioactive and anti-bacterial propertiescitations
- 2024Higher Laser power improves strength but reduces corrosion resistance of Mg WE43 processed by powder bed fusioncitations
- 2023Fe and C additions decrease the dissolution rate of silicon nitride coatings and are compatible with microglial viability in 3D collagen hydrogels
- 2023Fully 3D-printed PVDF-TrFE based piezoelectric devices with PVDF-TrFE-rGO composites as electrodescitations
- 2022An Enhanced Understanding of the Powder Bed Fusion-Laser Beam Processing of Mg-Y-3.9wt%-Nd-3wt%-Zr-0.5wt% (WE43) Alloy through Thermodynamic Modeling and Experimental Characterizationcitations
- 2022An ex-vivo model for the biomechanical assessment of cement discoplastycitations
- 2022Microstructural Origins of the Corrosion Resistance of a Mg-Y-Nd-Zr Alloy Processed by Powder Bed Fusion - Laser Beamcitations
- 2022Functionalized silk promotes cell migration into calcium phosphate cements by providing macropores and cell adhesion motifscitations
- 2022Biocompatibility of a Zr-Based Metallic Glass Enabled by Additive Manufacturingcitations
- 2022The Effect of PCL Addition on 3D-Printable PLA/HA Composite Filaments for the Treatment of Bone Defectscitations
- 2022Tailoring the dissolution rate and in vitro cell response of silicon nitride coatings through combinatorial sputtering with chromium and niobiumcitations
- 2022Composite poly(L-lactic acid) - ceramic structures for fully degradable cranial implants
- 2022Current status and future potential of wear-resistant coatings and articulating surfaces for hip and knee implantscitations
- 2020The effect of N, C, Cr, and Nb content on silicon nitride coatings for joint applicationscitations
- 2020The Effect of N, C, Cr, and Nb Content on Silicon Nitride Coatings for Joint Applicationscitations
- 2020Mechanical behaviour of composite calcium phosphate-titanium cranial implants : Effects of loading rate and designcitations
- 2018Heparinization of Beta Tricalcium Phosphate: Osteo‐immunomodulatory Effectscitations
- 2018Osteogenesis by foamed and 3D-printed nanostructured calcium phosphate scaffolds: Effect of pore architecturecitations
- 2017A novel strategy to enhance interfacial adhesion in fiber-reinforced calcium phosphate cementcitations
- 2017A novel strategy to enhance interfacial adhesion in fiber-reinforced calcium phosphate cementcitations
- 2017Osteoinduction by Foamed and 3D-Printed Calcium Phosphate Scaffolds: Effect of Nanostructure and Pore Architecturecitations
- 2017Elastic properties and strain-to-crack-initiation of calcium phosphate bone cements: Revelations of a high-resolution measurement techniquecitations
- 2016Dissolution behaviour of silicon nitride coatings for joint replacementscitations
- 2015Inflammatory response to nano- and microstructured hydroxyapatitecitations
- 2015Can Cobalt(II) and Chromium(III) Ions Released from Joint Prostheses Influence the Friction Coefficientcitations
- 2013Structure and composition of silicon nitride and silicon carbon nitride coatings for joint replacementscitations
- 2010Synthesis and characterization of injectable composites of poly[D,L-lactide-co-(ε-caprolactone)] reinforced with β-TCP and CaCO3 for intervertebral disk augmentationcitations
Places of action
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article
An ex-vivo model for the biomechanical assessment of cement discoplasty
Abstract
<jats:p>Percutaneous Cement Discoplasty (PCD) is a surgical technique developed to relieve pain in patients with advanced degenerative disc disease characterized by a vacuum phenomenon. It has been hypothesized that injecting bone cement into the disc improves the overall stability of the spinal segment. However, there is limited knowledge on the biomechanics of the spine postoperatively and a lack of models to assess the effect of PCD <jats:italic>ex-vivo</jats:italic>. This study aimed to develop a biomechanical model to study PCD in a repeatable and clinically relevant manner. Eleven ovine functional spinal units were dissected and tested under compression in three conditions: healthy, injured and treated. Injury was induced by a papain buffer and the treatment was conducted using PMMA cement. Each sample was scanned with micro-computed tomography (CT) and segmented for the three conditions. Similar cement volumes (in %) were injected in the ovine samples compared to volumes measured on clinical PCD CT images. Anterior and posterior disc heights decreased on average by 22.5% and 23.9% after injury. After treatment, the anterior and posterior disc height was restored on average to 98.5% and 83.6%, respectively, of their original healthy height. Compression testing showed a similar stiffness behavior between samples in the same group. A decrease of 51.5% in segment stiffness was found after injury, as expected. The following PCD treatment was found to result in a restoration of stiffness—showing only a difference of 5% in comparison to the uninjured state. The developed <jats:italic>ex-vivo</jats:italic> model gave an adequate representation of the clinical vacuum phenomena in terms of volume, and a repeatable mechanical response between samples. Discoplasty treatment was found to give a restoration in stiffness after injury. The data presented confirm the effectiveness of the PCD procedure in terms of restoration of axial stiffness in the spinal segment. The model can be used in the future to test more complex loading scenarios, novel materials, and different surgical techniques.</jats:p>