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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Cuschieri, Alfred
University of Dundee
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (11/11 displayed)
- 2018Design of a 2 DOFs Mini Hollow Joint Actuated with SMA Wirescitations
- 2017Low power consumption mini rotary actuator with SMA wirescitations
- 2016Liver retraction system by C3-muco-adhesive polymer films for laparoscopic surgerycitations
- 2016Analysis of performance and energy efficiency of thin shape memory alloy wire-based actuators
- 2016A variable impedance actuator using shape memory alloy
- 2015Complaint actuator
- 2014Mucoadhesive polymer films for tissue retraction in laparoscopic surgerycitations
- 2014Mucoadhesive polymer films for tissue retraction in laparoscopic surgery : ex-vivo study on their mechanical propertiescitations
- 2014Mucoadhesive polymer films for tissue retraction in laparoscopic surgery:ex-vivo study on their mechanical propertiescitations
- 2013Neuronal cells loaded with PEI-coated Fe 3 O 4 nanoparticles for magnetically guided nerve regenerationcitations
- 2013Neuronal cells loaded with PEI-coated Fe3O4 nanoparticles for magnetically guided nerve regenerationcitations
Places of action
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article
Mucoadhesive polymer films for tissue retraction in laparoscopic surgery
Abstract
Safe and effective manipulation of soft tissue during laparoscopic procedures can be achieved by the use of mucoadhesive polymer films. A series of novel adhesive polymer films were formulated in house based on either Carbopol or Chitosan modified systems. The mechanical properties of the polymers and their adherence to bowel were evaluated using ex-vivo pig bowel immersed in 37°C water bath and connected to an Instron tensiometer. Young's modulus was 300 kPa for the Carbopol-polymer and 5 kPa for the Chitosan-polymer. The Chitosan-polymer exhibited much larger shear adhesion than its tensile adhesion: 3.4 N vs. 1.2. Both tensile and shear adhesions contributed to the large retraction force (2.6 N) obtained during l polymer-bowel retraction testing. Work of adhesion at the polymer/serosa interface, defined as the area under the force curve, was 64 mJ, which is appreciably larger than that reported with existing polymers. In conclusion, adhesive polymers can stick to the serosal side of the bowel with an adhesive force, which is sufficient to lift the bowel, providing a lower retraction stress than that caused by laparoscopic grasping which induces high localized pressures on the tissue.