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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Akhtar, Riaz
University of Liverpool
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (14/14 displayed)
- 2022Ligament mechanics of ageing and osteoarthritic human kneescitations
- 2018Facile production of nanocomposites of carbon nanotubes and polycaprolactone with high aspect ratios with potential applications in drug deliverycitations
- 2017Dual-stimuli responsive injectable microgel/solid drug nanoparticle nanocomposites for release of poorly soluble drugscitations
- 2016A pilot study of scanning acoustic microscopy as a tool for measuring arterial stiffness in aortic biopsiescitations
- 2015Using intermolecular interactions to crosslink PIM- 1 and modify its gas sorption properties
- 2015Using intermolecular interactions to crosslink PIM-1 and modify its gas sorption propertiescitations
- 2015Biomechanical Changes of Collagen Cross-Linking on Human Keratoconic Corneas Using Scanning Acoustic Microscopy.citations
- 2014Biomechanical changes after repeated collagen cross-linking on human corneas assessed in vitro using scanning acoustic microscopycitations
- 2013Biomechanical properties of human corneas following low- and high-intensity collagen cross-linking determined with scanning acoustic microscopycitations
- 2013Scanning acoustic microscopy for mapping the microelastic properties of human corneal tissuecitations
- 2012Multi-layer phase analysis: Quantifying the elastic properties of soft tissues and live cells with ultra-high-frequency scanning acoustic microscopycitations
- 2011Quantifying micro-mechanical properties of soft biological tissues with scanning acoustic microscopycitations
- 2008Mapping the Micromechanical Properties of Cryo-sectioned Aortic Tissue with Scanning Acoustic Microscopycitations
- 2008Nanoindentation of histological specimens using an extension of the Oliver and Pharr methodcitations
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article
Biomechanical Changes of Collagen Cross-Linking on Human Keratoconic Corneas Using Scanning Acoustic Microscopy.
Abstract
PURPOSE: To assess the biomechanical changes of collagen cross-linking on keratoconic corneas in vitro. METHODS: Six keratoconic corneal buttons were included in this study. Each cornea was divided into two halves, where one half was cross-linked and the other half was treated with riboflavin only and served as control. The biomechanical changes of the corneal tissue were measured across the stroma using scanning acoustic microscopy (SAM). RESULTS: In the cross-linked corneas, there was a steady decrease in the magnitude of speed of sound from the anterior region through to the posterior regions of the stroma. The speed of sound was found to decrease slightly across the corneal thickness in the control corneas. The increase in speed of sound between the cross-linked and control corneas in the anterior region was by a factor of 1.039×. CONCLUSION: A higher speed of sound was detected in cross-linked keratoconic corneal tissue when compared with their controls, using SAM. This in vitro model can be used to compare to the cross-linking results obtained in vivo, as well as comparing the results obtained with different protocols.