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| Azevedo, Nuno Monteiro |
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Trzaskowski, Maciej
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article
Polyvinylpyrrolidone-based coatings for polyurethanes - the effect of reagent concentration on their chosen physical properties
Abstract
A method of manufacturing hydrogel coatings designed to increase the hydrophilicity ofpolyurethanes (PU) is presented. Coatings were obtained from polyvinylpyrrolidone (PVP) by freeradical polymerisation. The authors proposed a mechanism of a two-step grafting – crosslinkingprocess and investigated the influence of reagent concentration on the coating’s physical properties -hydrogel ratio (HG) and equilibrium swelling ratio (ESR). A surface analysis of freeze-driedcoatings using scanning electron microscopy (SEM) showed a highly porous structure. Thepresented technology can be used to produce biocompatible surfaces with limited protein and celladhesive properties and can be applied in fabrication of number of biomedical devices, e.g.catheters, vascular grafts and heart prosthesis.