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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Hampel, Silke
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (14/14 displayed)
- 2024ZnO–Graphene Oxide Nanocomposite for Paclitaxel Delivery and Enhanced Toxicity in Breast Cancer Cells
- 2023Facile one-pot hydrothermal synthesis of a zinc oxide/curcumin nanocomposite with enhanced toxic activity against breast cancer cells
- 2020Synthesis of $(Li_{2}Fe_{1–y}Mn_{y})SO$ Antiperovskites with Comprehensive Investigations of $(Li_{2}Fe_{0.5}Mn_{0.5})SO$ as Cathode in Li-ion Batteriescitations
- 2020Filled carbon nanotubes as anode materials for lithium-ion batteriescitations
- 2020Nitrogen-Doped Carbon Nanotube/Polypropylene Composites with Negative Seebeck Coefficient
- 2019Chromium Trihalides CrX3 (X = Cl, Br, I): Direct Deposition of Micro- and Nanosheets on Substrates by Chemical Vapor Transport
- 2018Electro-responsive graphene oxide hydrogels for skin bandages: The outcome of gelatin and trypsin immobilizationcitations
- 2015Mechanical reinforcement of copper films with ceramic nanoparticlescitations
- 2015Recent advances in the synthesis and biomedical applications of nanocomposite hydrogels
- 2014Fabrication of nanoparticle-containing films and nano layers for alloying and joiningcitations
- 2013Loss spectroscopy of molecular solids: combining experiment and theorycitations
- 2010Carbon nanotubes filled with ferromagnetic materials
- 2008Carbon nanotubes filled with a chemotherapeutic agent: a nanocarrier mediates inhibition of tumor cell growthcitations
- 2006Synthesen, Eigenschaften und Kristallstrukturen der Cluster-Salze Bi 6[PtBi6Cl12] und Bi2/3[PtBi 6Cl12]citations
Places of action
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article
Carbon nanotubes filled with a chemotherapeutic agent: a nanocarrier mediates inhibition of tumor cell growth
Abstract
<jats:p> Aim: In this paper, carbon nanotubes (CNTs) are presented as feasible carriers for carboplatin, a therapeutic agent for cancer treatment. The drug was introduced into CNTs to demonstrate that they are suited as nanocontainers and nanocarriers and can release the drug to initialize its medical virtue. Method: The filling was accomplished by a wet-chemical approach after the CNTs were opened. The effect on cell proliferation and cytotoxicity of the carboplatin-filled CNT was investigated by using a viability assays. Results: Using different analysis methods such as electron energy loss spectroscopy and x-ray photoelectron spectroscopy the structure of carboplatin incorporated into the CNTs was found to be retained. In vitro studies showed that carboplatin-filled CNTs inhibited growth of bladder cancer cells whereas unfilled, opened CNTs barely affected cancer cell growth. Conclusion: A reversible filling–emptying process could be performed successfully within this work. This highlights the potential of CNTs for applications in the field of drug delivery. </jats:p>